ULK2 产品
(Unc-51 Like Kinase 2 (ULK2))
Categories
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008].
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Featured ULK2 Categories
Recommended ULK2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, ICC, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN2856810
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (5)
Cat. No.
ABIN5542414
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7169209
Quantity
100 μg
Datasheet
Datasheet
Recommended ULK2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324623
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3096205
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509192
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ULK2 Products
: "TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy." in: Nature communications, Vol. 11, Issue 1, pp. 770, (2020) (PubMed).: "Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response." in: The Journal of biological chemistry, Vol. 292, Issue 34, pp. 14050-14065, (2017) (PubMed).
: "Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism." in: Nature, Vol. 524, Issue 7565, pp. 361-5, (2015) (PubMed).
: "Methylation silencing of ULK2, an autophagy gene, is essential for astrocyte transformation and tumor growth." in: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22306-18, (2014) (PubMed).
: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).
: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).
: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." in: Oncogene, Vol. 18, Issue 43, pp. 5850-9, (1999) (PubMed).
: "Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts." in: Cell, Vol. 89, Issue 5, pp. 755-64, (1997) (PubMed).
Synonyms and alternative names related to ULK2
unc-51 like autophagy activating kinase 2 (ULK2), unc-51 like autophagy activating kinase 2 (Ulk2), unc-51 like kinase 2 (Ulk2), unc-51 like autophagy activating kinase 2 (ulk2), A830085I22Rik, ATG1B, AU015340, mKIAA0623, ULK2, Unc51.2Protein level used designations for ULK2
- unc-51-like kinase 2 (C. elegans)
- serine/threonine-protein kinase ULK2
- Unc-51 like kinase 2
- serine/threonine-protein kinase Unc51.2
- unc-51-like kinase 2
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