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ULK2 抗体 (AA 211-276)

ULK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169209
发货至: 中国
  • 抗原 See all ULK2 抗体
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    抗原表位
    • 12
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-276
    适用
    • 64
    • 18
    • 8
    宿主
    • 56
    • 9
    克隆类型
    • 57
    • 8
    多克隆
    标记
    • 34
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    This ULK2 antibody is un-conjugated
    应用范围
    • 49
    • 44
    • 14
    • 11
    • 10
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Serine/threonine-protein kinase ULK2 protein (211-276AA)
    亚型
    IgG
    Top Product
    Discover our top product ULK2 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    别名
    ULK2 (ULK2 产品)
    别名
    ULK2 antibody, ATG1B antibody, Unc51.2 antibody, A830085I22Rik antibody, AU015340 antibody, mKIAA0623 antibody, unc-51 like autophagy activating kinase 2 antibody, unc-51 like kinase 2 antibody, ULK2 antibody, Ulk2 antibody, ulk2 antibody
    背景

    Background: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR, however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons.

    Aliases: ATG1B antibody, KIAA0623 antibody, Serine/threonine protein kinase ULK2 antibody, Serine/threonine-protein kinase ULK2 antibody, ULK2 antibody, ULK2_HUMAN antibody, Unc 51 (C. elegans) like kinase 2 antibody, Unc 51 like autophagy activating kinase 2 antibody, Unc 51 like kinase 2 antibody, Unc-51-like kinase 2 antibody, Unc51.2 antibody

    UniProt
    Q8IYT8
    途径
    Regulation of Cell Size, Autophagy
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