UBE2L6 产品
(Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011].
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Featured UBE2L6 Categories
Recommended UBE2L6 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN563994
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7257289
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6149808
Quantity
100 μL
Datasheet
Datasheet
Recommended UBE2L6 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6222131
Quantity
96 tests
Datasheet
Datasheet
Recommended UBE2L6 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7544895
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125622
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667729
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our UBE2L6 Products
: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." in: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).: "Bortezomib Causes ER Stress-related Death of Acute Promyelocytic Leukemia Cells Through Excessive Accumulation of PML-RARA." in: Anticancer research, Vol. 35, Issue 6, pp. 3307-16, (2015) (PubMed).
: "Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 132-8, (2011) (PubMed).
: "Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cells." in: Journal of virology, Vol. 83, Issue 12, pp. 5971-7, (2009) (PubMed).
: "Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury." in: FEBS letters, Vol. 582, Issue 13, pp. 1802-8, (2008) (PubMed).
: "TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels." in: Nucleic acids research, Vol. 36, Issue 12, pp. 4067-78, (2008) (PubMed).
: "Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 5, pp. 1369-79, (2008) (PubMed).
: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." in: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).
: "Genomic organization of the human ubiquitin-conjugating enzyme gene, UBE2L6 on chromosome 11q12." in: Cytogenetics and cell genetics, Vol. 89, Issue 1-2, pp. 137-40, (2000) (PubMed).
: "Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13548-54, (1997) (PubMed).
Synonyms and alternative names related to UBE2L6
ubiquitin conjugating enzyme E2 L6 (UBE2L6), ubiquitin-conjugating enzyme E2L 6 (Ube2l6), 2810489I21Rik, RIG-B, Ubce8, UBCH8, Ubcm8, UbcM8, UBE2L6Protein level used designations for UBE2L6
- ubiquitin-conjugating enzyme E2L 6
- ubiquitin/ISG15-conjugating enzyme E2 L6
- retinoic acid induced gene B protein
- retinoic acid-induced gene B protein
- ubiquitin carrier protein L6
- ubiquitin-protein ligase L6
- E2 ubiquitin conjugating enzyme
- ubiquitin-conjugating enzyme 8
- ubcM8
- Ubiquitin carrier protein L6
- Ubiquitin-protein ligase L6
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