anti-CD4 (CD4) 抗体产品概述

Full name:: anti-CD4 Molecule 抗体 (CD4)

在www.antibodies-online.cn可供2347 CD4 Molecule (CD4) 抗体的45不同的供货商。再加上，我们可以发CD4 试剂盒 (73) 和 CD4 蛋白 (69)和数多这个蛋白质的别的产品。总共2514 CD4产品已列进来了。

别名:: cd4, CD4mut, L3T4, Ly-4, p55, W3/25

列出全部抗体	基因	基因ID	UniProt
抗小鼠 CD4	CD4	12504	P06332
抗人 CD4	CD4	920	P01730
抗大鼠 CD4	CD4	24932	P05540
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抗Mouse (Murine) CD4 抗体:

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CXCR4-mediated Signaling Events

引用最多的anti-CD4 抗体

Mouse (Murine) Monoclonal CD4 Primary Antibody for BR, IHC (f) - ABIN2689225 : Regnier-Vigouroux, Blanc, Pont, Marchetto, Pierres: Accessory molecules and T cell activation. I. Antigen receptor avidity differentially influences T cell sensitivity to inhibition by monoclonal antibodies to LFA-1 and L3T4. in European journal of immunology 1987 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689237 : Bendelac: Mouse NK1+ T cells. in Current opinion in immunology 1995 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for BR, CyTox - ABIN1176846 : Bierer, Sleckman, Ratnofsky, Burakoff: The biologic roles of CD2, CD4, and CD8 in T-cell activation. in Annual review of immunology 1989 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for IHC (f), IHC (fro) - ABIN2689224 : Allman, Li, Hardy: Commitment to the B lymphoid lineage occurs before DH-JH recombination. in The Journal of experimental medicine 1999 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689236 : Bosselut, Zhang, Ashe, Kopacz, Samelson, Singer: Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction. in The Journal of experimental medicine 1999 (PubMed)
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Dog (Canine) Polyclonal CD4 Primary Antibody for ICC, IF - ABIN439030 : Hwang, Ahn, Park, Ha, Song, Jee: An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells. in Immunology letters 2011 (PubMed)
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Human Monoclonal CD4 Primary Antibody for BP, FACS - ABIN4292796 : Wilson, Crowley, Odgers, Shaw: Immunofluorescent labeling using covalently linked anti-phycoerythrin antibodies and phycoerythrin polymers. in Cytometry 1991 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689238 : Frederickson, Basch: L3T4 antigen expression by hemopoietic precursor cells. in The Journal of experimental medicine 1989 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689223 : Godfrey, Kennedy, Mombaerts, Tonegawa, Zlotnik: Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. in Journal of immunology (Baltimore, Md. : 1950) 1994 (PubMed)
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Rat (Rattus) Monoclonal CD4 Primary Antibody for ICC, FACS - ABIN2749065 : Viel, Lemarié, Benkirane, Paradis, Schiffrin: Immune regulation and vascular inflammation in genetic hypertension. in American journal of physiology. Heart and circulatory physiology 2010 (PubMed)
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更多抗CD4的相互作用对抗体

Mouse (Murine) CD4 Molecule (CD4) interaction partners

data showed the critical role of the first extracellular domain of CD4, by obtaining mice with a loss of function mutation from Ile to Asn at the position 99 of CD4 (I99N).
results suggest that CD4 CD8 (显示 CD8A 抗体) double knockout (DN)T cells can develop efficiently in vivo and chronic exposure to bacterial superantigens may precipitate a lupus-like autoimmune disease through activation of DNT (显示 NT5C 抗体) cells
TCF-1-deficient CD4+ CD8+ double positive thymocytes fail to undergo TCR alpha Valpha14-Jalpha18 rearrangement and produce significantly fewer Natural killer T cells.
High-fat diet - induced type 2 diabetes decreases the number of ileum IL17 (显示 IL17A 抗体)/RORgammaT CD4 T cells.
Results indicate that hypomethylation of Cd4 antigen correlates with stable CD4 expression.
CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase (显示 YES1 抗体) p56lck (显示 LCK 抗体)
This study establishes an important role of IgE in abdominal aortic aneurysms pathogenesis by activating CD4+ T cells, mast cells, and macrophages.
5-kb cis (显示 CISH 抗体)-element is required in postselection thymocytes for helper lineage commitment, presumably mediating the maintenance of CD4 expression, and suggest that inactivation of the cis (显示 CISH 抗体)-element by DNA methylation (显示 HELLS 抗体)
Both type I CD8 (显示 CD8A 抗体)+ cytotoxic (Tc1 (显示 C8orf4 抗体)) cells and interleukin (IL)-17 (显示 IL17A 抗体)-producing CD8 (显示 CD8A 抗体)+ (Tc17) cells mediate effective antitumor immunity through distinct effector mechanisms, but Tc1 (显示 C8orf4 抗体) cells are superior to Tc17 cells in mediating tumor regression.
Accumulation of CD4 positive effector T cells is a critical step in the progression from mild glomerulonephritis to severe crescentic glomerulonephritis accompanied by tubulointerstitial inflammation and loss of kidney function.

Human CD4 Molecule (CD4) interaction partners

CD4(+) and CD19 (显示 CD19 抗体)(+) peripheral lymphocytes of early stage AD patients exhibit mitochondrial depletion, as seen both at the level of DNA and protein
Human microRNAs-221 and -222 inhibit HIV-1 entry in macrophages by targeting the CD4 viral receptor.
CD4 has four ecto (显示 TRIM33 抗体)-domains (D1-D4), D1, D2, and D4 each contain a distinctive disulfide bond. Reduction of D2 disulfide decreases the dynamics of its surrounding beta-strands. Favorable inward collapse of structure occurs around the D2 disulfide after reduction.
Long-term lung function decline in asthma is associated with elevation of bronchial CD8 and CD4 at baseline, and CD8, CD3 and granzyme B at follow-up
Our results indicate that CD4 expression and older age are adverse prognostic factors in wild-type NPM1 (显示 NPM1 抗体), FLT3 (显示 FLT3 抗体)-ITD-negative CN-AML (显示 RUNX1 抗体).
We investigated the prevalence, magnitude and phenotype of CTAg (显示 CTAG1B 抗体)-specific T cells in the blood of patients with testicular germ cell tumors (TGCTs). CD8 (显示 CD8A 抗体)(+) and CD4(+) T-cell responses against MAGE (显示 MAGEB10 抗体)-A family antigens were present in 44% (20/45) of patients' samples assayed by ex vivo IFN-gamma (显示 IFNG 抗体) ELISPOT. Spontaneous T-cell immunity against CTAg (显示 CTAG1B 抗体) proteins therefore develops in many patients with testicular cancer.
Depletion of the gamma2 or mu1A (AP1M1 (显示 AP1M1 抗体)) subunits of AP-1 (显示 FOSB 抗体), but not of gamma1 (AP1G1 (显示 AP1G1 抗体)), precludes Nef-mediated lysosomal degradation of CD4.
findings provide a mechanistic explanation for previous observations that dimerization-defective Nef mutants fail to down-regulate CD4 and validate the Nef dimerization interface as a target site for antiretroviral drug development
Mouse leukemia cell lines that could express hCD4 and CCR5 were thus established to facilitate normal entry of HIV-1 so that a human CD4/CCR5 transgenic mice cell model can be used to investigate the transmission and pathogenesis of HIV/AIDS and potential antiviral drugs against this disease.
The percentage of lamina propia CD4+LAP+ cells is increased in active ulcerative colitis, showing reduced suppressor activity due to their increased proportion of intracellular IL-17 (显示 IL17A 抗体) expression.

Pig (Porcine) CD4 Molecule (CD4) interaction partners

The frequency and expression of a CD4 variant in microminipigs are described.
These data help clarify the regulatory mechanism of DNA methylation (显示 HELLS 抗体) of the CD4 gene in non-immune cell response to virus replication.

Cow (Bovine) CD4 Molecule (CD4) interaction partners

These results suggest that CD4 plays a role in production traits as well as in immune function. The identified SNPs could be used as genetic markers for selection of dairy cows with improved fat percentage. We propose further studies of these SNPs in a larger population as well as further investigations of the function of this gene.
These results suggested that the SNPs in CD4 and STAT5b (显示 STAT5B 抗体) may be potential genetic markers for SCS (显示 TWIST1 抗体) and milk/protein (显示 CSN2 抗体) yields selecting and warrant further functional research.
The DNA methylation (显示 HELLS 抗体) level of the CD4 gene was strongly influenced by mastitis in Chinese Holstein cattle.
These findings revealed that despite the existence of a distinct bovine CD4(+)CD25 (显示 IL2RA 抗体)(high) T cell population, which showed Foxp3 (显示 FOXP3 抗体) transcription/expression, natural regulatory activity did not reside in this cell population

Rhesus Monkey CD4 Molecule (CD4) interaction partners

The absence of CD4 T cells results in failure to produce antibodies that neutralize CD4-independent SIV Envs and CD4-pretriggered control SIV Envs.

Chimpanzee CD4 Molecule (CD4) interaction partners

study found noticeable variation in the first variable region V1 of CD4 and in intron six among the subspecies of chimpanzees.

CD4 抗原简介

Antigen Summary

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Alternative names and synonyms associated with CD4

CD4 molecule (CD4) 抗体
carcinoembryonic antigen-related cell adhesion molecule 5 (LOC100125525) 抗体
T-cell surface glycoprotein CD4 (cd4) 抗体
CD4 antigen (Cd4) 抗体
Cd4 molecule (Cd4) 抗体
CD4 molecule (Cd4) 抗体

cd4 抗体
CD4mut 抗体
L3T4 抗体
Ly-4 抗体
p55 抗体
W3/25 抗体

Protein level used designations for anti-CD4 Molecule (CD4) 抗体

CD4 antigen , T-cell surface glycoprotein CD4 , T-cell differentiation antigen L3T4 , T-cell surface antigen T4/Leu-3 , T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4) , CD4 antigen (p55) , CD4 receptor , W3/25 antigen , lymphocyte antigen CD4 , cell surface glycoprotein CD4

GENE ID	SPECIES
100016045	Monodelphis domestica
100125525	Oryzias latipes
778001	Takifugu rubripes
100286469	Salmo salar
12504	Mus musculus
920	Homo sapiens
24932	Rattus norvegicus
101790140	Anas platyrhynchos
493775	Felis catus
404704	Sus scrofa
395362	Gallus gallus
403931	Canis lupus familiaris
443509	Ovis aries
407098	Bos taurus
100734494	Cavia porcellus
100009152	Oryctolagus cuniculus
100126554	Meleagris gallopavo
713807	Macaca mulatta
450124	Pan troglodytes

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