CD42b 抗体
(Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].
recommended
GP1BA 适用: 人 FACS, WB, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6H6H10 unconjugated
recommended
recommended
CD42b 抗体 by 适用
Find CD42b 抗体 for a variety of species such as anti-Human CD42b, anti-Mouse CD42b, anti-Rat CD42b. The species listed below are among those available. Click on a link to go to the corresponding products.
CD42b 抗体 by 抗体来源
Find CD42b 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
CD42b 抗体 by 克隆形成能力
Find available monoclonal or polyclonal CD42b 抗体. Click on a link to go to the corresponding products.
CD42b 抗体 by 克隆
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CD42b 抗体 by 标记
Find CD42b 抗体 with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular CD42b 抗体
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Validations
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Datasheet
Reactivity
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Application
FACS, WB, IHC, ELISA, ICC, Neut
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
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Cat. No.
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Quantity
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Application
FACS, WB, ELISA, IP, ICC
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Cat. No.
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Quantity
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Datasheet
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Latest Publications for our CD42b 抗体
: "GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate." in: Journal of thrombosis and haemostasis : JTH, (2023) (PubMed).: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." in: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).
: "Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation." in: Haematologica, (2019) (PubMed).
: "Temperature effects on the activity, shape, and storage of platelets from 13-lined ground squirrels." in: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol. 187, Issue 5-6, pp. 815-825, (2017) (PubMed).
: "Nanoparticle biointerfacing by platelet membrane cloaking." in: Nature, Vol. 526, Issue 7571, pp. 118-21, (2015) (PubMed).
: "Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylation." in: The Journal of experimental medicine, (2014) (PubMed).
: "Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse." in: Journal of thrombosis and haemostasis : JTH, Vol. 10, Issue 11, pp. 2344-53, (2014) (PubMed).
: "The collagen-binding integrin α2β1 is a novel interaction partner of the Trimeresurus flavoviridis venom protein flavocetin-A." in: The Journal of biological chemistry, Vol. 288, Issue 2, pp. 947-55, (2013) (PubMed).
: "Expression of megakaryocytic and myeloid markers in blasts of transient abnormal myelopoiesis in a stillbirth with Down syndrome: report of histopathological findings of an autopsy case." in: Human pathology, Vol. 42, Issue 1, pp. 141-5, (2010) (PubMed).
: "Novel point mutation in a leucine-rich repeat of the GPIbalpha chain of the platelet von Willebrand factor receptor, GPIb/IX/V, resulting in an inherited dominant form of Bernard-Soulier syndrome ..." in: Haematologica, Vol. 93, Issue 11, pp. 1743-7, (2008) (PubMed).
Aliases for CD42b 抗体
glycoprotein Ib platelet alpha subunit (GP1BA) 抗体glycoprotein Ib (platelet), alpha polypeptide (GP1BA) 抗体
glycoprotein Ib platelet alpha subunit (Gp1ba) 抗体
glycoprotein 1b, alpha polypeptide (Gp1ba) 抗体
BDPLT1 抗体
BDPLT3 抗体
BSS 抗体
CD42B 抗体
CD42b-alpha 抗体
DBPLT3 抗体
GP1B 抗体
GP1BA 抗体
GPIbA 抗体
GPIba 抗体
GPIbalpha 抗体
VWDP 抗体
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