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CD42b 抗体

GP1BA 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HIP1 unconjugated
产品编号 ABIN94113
发货至: 中国
  • 抗原 See all CD42b (GP1BA) 抗体
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    适用
    • 69
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    • 1
    • 1
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    人, Non-Human Primate
    宿主
    • 36
    • 33
    • 2
    小鼠
    克隆类型
    • 39
    • 32
    单克隆
    标记
    • 39
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This CD42b antibody is un-conjugated
    应用范围
    • 34
    • 32
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    • 6
    • 4
    • 2
    • 1
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The antibody HIP1 reacts with an extracellular epitope of CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c, 160 kDa), CD42b/c forms a noncovalent complex with CD42a and CD42d.
    交叉反应 (详细)
    Human, Non-Human Primates
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Peripheral blood mononuclear cells of a patient suffering with CLL.
    克隆位点
    HIP1
    亚型
    IgG1
    Top Product
    Discover our top product GP1BA Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    别名
    CD42b (GP1BA 产品)
    别名
    BDPLT1 antibody, BDPLT3 antibody, BSS antibody, CD42B antibody, CD42b-alpha antibody, DBPLT3 antibody, GP1B antibody, GPIbA antibody, VWDP antibody, GP1BA antibody, GPIba antibody, GPIbalpha antibody, glycoprotein Ib platelet alpha subunit antibody, glycoprotein Ib (platelet), alpha polypeptide antibody, glycoprotein 1b, alpha polypeptide antibody, GP1BA antibody, Gp1ba antibody
    背景
    Glycoprotein Ib platelet subunit alpha,CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.,BSS, GP1B, VWDP, CD42B, GPIbA, BDPLT1, BDPLT3, DBPLT3
    基因ID
    2811
    UniProt
    P07359
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