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CD46 抗体

(CD46)
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].
CD46 抗体  (AA 317-343) CD46 抗体  (AA 317-343) CD46 抗体 (AA 317-343) (ABIN3030405)

CD46 适用: 人 FACS, IF, IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated

CD46 抗体 CD46 抗体 CD46 抗体 (ABIN125715)

CD46 适用: 人, Cow FACS, IP, WB 宿主: 小鼠 Monoclonal MEM-258 unconjugated

CD46 抗体 CD46 抗体 CD46 抗体 (ABIN94149)

CD46 适用: 人, Cow FACS, IP, WB 宿主: 小鼠 Monoclonal MEM-258 unconjugated

CD46 抗体 by 适用

Find CD46 抗体 for a variety of species such as anti-Human CD46, anti-Mouse CD46, anti-Rat CD46. The species listed below are among those available. Click on a link to go to the corresponding products.

CD46 抗体 by 应用范围

Find CD46 抗体 validated for a specific application such as FACS, WB, IF, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CD46 抗体 by 抗体来源

Find CD46 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

CD46 抗体 by 抗原表位

Find CD46 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CD46 抗体 by 克隆形成能力

Find available monoclonal or polyclonal CD46 抗体. Click on a link to go to the corresponding products.

CD46 抗体 by 克隆

Find CD46 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

CD46 抗体 by 标记

Find CD46 抗体 with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CD46 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (4)
Cat. No. ABIN687832
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7127403
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human
Application FACS, IP, WB
Validations
  • (9)
  • (2)
Cat. No. ABIN94151
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Cow, Human
Application FACS, IP, WB
Validations
  • (7)
  • (2)
Cat. No. ABIN94152
Quantity 100 tests
Datasheet Datasheet
Reactivity Cow, Human
Application FACS, IP, WB
Validations
  • (7)
  • (2)
Cat. No. ABIN192263
Quantity 100 tests
Datasheet Datasheet
Reactivity Mouse
Application ICC, IHC, WB
Validations
  • (3)
Cat. No. ABIN1859778
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IP
Validations
  • (3)
Cat. No. ABIN1449263
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7159320
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7177453
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7233504
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (2)
Cat. No. ABIN7257098
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (2)
Cat. No. ABIN7092945
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human
Application FACS, IP, WB
Validations
  • (9)
  • (1)
Cat. No. ABIN94153
Quantity 100 tests
Datasheet Datasheet
Reactivity Mouse
Application IA, IHC (fro), FACS, IF, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2191857
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS, Func, IF
Validations
  • (2)
Cat. No. ABIN6940026
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD46 抗体

Frolikova, Otcenaskova, Valasková, Postlerova, Stopkova, Stopka, Komrskova: "The Role of Taste Receptor mTAS1R3 in Chemical Communication of Gametes." in: International journal of molecular sciences, Vol. 21, Issue 7, (2020) (PubMed).

Martinez-Martin, Marcandalli, Huang, Arthur, Perotti, Foglierini, Ho, Dosey, Shriver, Payandeh, Leitner, Lanzavecchia, Perez, Ciferri: "An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor." in: Cell, Vol. 174, Issue 5, pp. 1158-1171.e19, (2019) (PubMed).

Ellinghaus, Cortini, Pinder, Le Friec, Kemper, Vyse: "Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus." in: European journal of immunology, Vol. 47, Issue 7, pp. 1200-1210, (2017) (PubMed).

Richter, Yumul, Saydaminova, Wang, Gough, Baldessari, Cattaneo, Lee, Wang, Jang, Astier, Gopal, Carter, Lieber: "Preclinical safety, pharmacokinetics, pharmacodynamics, and biodistribution studies with Ad35K++ protein: a novel rituximab cotherapeutic." in: Molecular therapy. Methods & clinical development, Vol. 5, pp. 16013, (2016) (PubMed).

Abbink, Maxfield, Nganga, Borducchi, Iampietro, Bricault, Teigler, Blackmore, Parenteau, Wagh, Handley, Zhao, Virgin, Korber, Barouch: "Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors." in: Journal of virology, Vol. 89, Issue 3, pp. 1512-22, (2015) (PubMed).

Sei, Mizuno, Suzuki, Imai, Higashide, Harris, Sakata, Iguchi, Fujiwara, Kodera, Maruyama, Matsuo, Ito: "Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy." in: Molecular immunology, Vol. 65, Issue 2, pp. 302-9, (2015) (PubMed).

Johnson, Borisevich, Rockx, Parks: "A novel factor I activity in Nipah virus inhibits human complement pathways through cleavage of C3b." in: Journal of virology, Vol. 89, Issue 2, pp. 989-98, (2015) (PubMed).

Miyaji, Paul, Shahrizaila, Umapathi, Yuki: "Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies?" in: Journal of neuroimmunology, Vol. 276, Issue 1-2, pp. 172-4, (2014) (PubMed).

Toivonen, Koskenvuo, Merentie, Söderström, Ylä-Herttuala, Savontaus: "Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5." in: Virology journal, Vol. 9, pp. 296, (2013) (PubMed).

Fett, Hermann, Muether, Kirchhof, Fauser: "Immunohistochemical localization of complement regulatory proteins in the human retina." in: Histology and histopathology, Vol. 27, Issue 3, pp. 357-64, (2012) (PubMed).

Aliases for CD46 抗体

CD46 molecule (CD46) 抗体
CD46 antigen, complement regulatory protein (Cd46) 抗体
CD46 molecule (Cd46) 抗体
CD46 molecule, complement regulatory protein (CD46) 抗体
membrane cofactor protein-like (LOC100341359) 抗体
membrane cofactor protein-like (LOC103789310) 抗体
AHUS2 抗体
CD46 抗体
MCP 抗体
Mcp 抗体
MIC10 抗体
TLX 抗体
TRA2.10 抗体
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