SLC22A1 抗体
(Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008].
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SLC22A1
适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, Pig
WB
宿主: 兔
Polyclonal
unconjugated
2 images
Latest Publications for our SLC22A1 抗体
: "Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB)." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173474, (2017) (PubMed).: "Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers." in: PLoS ONE, Vol. 12, Issue 6, pp. e0180257, (2017) (PubMed).
: "Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport." in: American journal of human genetics, Vol. 101, Issue 4, pp. 489-502, (2017) (PubMed).
: "The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin." in: Scientific reports, Vol. 6, pp. 20508, (2016) (PubMed).
: "Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1." in: Genome medicine, Vol. 7, Issue 1, pp. 56, (2015) (PubMed).
: "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier." in: Molecular pharmaceutics, Vol. 11, Issue 3, pp. 995-1006, (2014) (PubMed).
: "Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 6, pp. 990-5, (2014) (PubMed).
: "OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients." in: Leukemia & lymphoma, Vol. 49, Issue 11, pp. 2222-3, (2008) (PubMed).
: "Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells." in: Pharmaceutical research, Vol. 25, Issue 4, pp. 827-35, (2008) (PubMed).
: "Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia." in: Blood, Vol. 112, Issue 8, pp. 3348-54, (2008) (PubMed).
Aliases for SLC22A1 抗体
solute carrier family 22 member 1 (SLC22A1) 抗体solute carrier family 22 (organic cation transporter), member 1 (Slc22a1) 抗体
solute carrier family 22 member 1 (Slc22a1) 抗体
solute carrier family 22 member 2-like (LOC421584) 抗体
HOCT1 抗体
Lx1 抗体
OCT1 抗体
Oct1 抗体
oct1_cds 抗体
Orct 抗体
Orct1 抗体
Roct1 抗体
SLC22A1 抗体
SLC22A2 抗体
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