SLC12A3 抗体
(Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))
This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Recommended next Filters:
您想试用我们的人工智能搜索吗？
69 results
SLC12A3
适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our SLC12A3 抗体
: "Generating Multiple Kidney Progenitors and Cell Types from Human Pluripotent Stem Cells." in: Methods in molecular biology (Clifton, N.J.), Vol. 1926, pp. 103-115, (2019) (PubMed).: "A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation." in: Circulation research, Vol. 125, Issue 12, pp. 1055-1066, (2019) (PubMed).
: "Norepinephrine-Induced Stimulation of Kir4.1/Kir5.1 Is Required for the Activation of NaCl Transporter in Distal Convoluted Tubule." in: Hypertension (Dallas, Tex. : 1979), Vol. 73, Issue 1, pp. 112-120, (2019) (PubMed).
: "Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis." in: Kidney international, Vol. 92, Issue 2, pp. 397-414, (2018) (PubMed).
: "β3 adrenergic receptor in the kidney may be a new player in sympathetic regulation of renal function." in: Kidney international, Vol. 90, Issue 3, pp. 555-67, (2017) (PubMed).
: "Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys." in: Journal of extracellular vesicles, Vol. 5, pp. 29642, (2016) (PubMed).
: "The Role of Epithelial Sodium Channel ENaC and the Apical Cl-/HCO3- Exchanger Pendrin in Compensatory Salt Reabsorption in the Setting of Na-Cl Cotransporter (NCC) Inactivation." in: PLoS ONE, Vol. 11, Issue 3, pp. e0150918, (2016) (PubMed).
: "Tenofovir during pregnancy in rats: a novel pathway for programmed hypertension in the offspring." in: The Journal of antimicrobial chemotherapy, Vol. 70, Issue 4, pp. 1094-105, (2015) (PubMed).
: "Increased Epithelial Sodium Channel Activity Contributes to Hypertension Caused by Na+-HCO3- Cotransporter Electrogenic 2 Deficiency." in: Hypertension, Vol. 66, Issue 1, pp. 68-74, (2015) (PubMed).
: "A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells." in: Scientific reports, Vol. 5, pp. 12829, (2015) (PubMed).
Aliases for SLC12A3 抗体
solute carrier family 12 member 3 (SLC12A3) 抗体solute carrier family 12 (sodium/chloride transporter), member 3 (slc12a3.2) 抗体
solute carrier family 12 member 3 (Slc12a3) 抗体
solute carrier family 12, member 3 (Slc12a3) 抗体
AI035291 抗体
DKFZp469N2315 抗体
NCC 抗体
NCCT 抗体
SLC12A3 抗体
slc12a3 抗体
TSC 抗体
您还需要查找其他产品吗？
You are here:
