SIPA1 抗体
(Signal-Induced Proliferation-Associated 1 (SIPA1))
The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008].
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Latest Publications for our SIPA1 抗体
: "Bromodomain protein Brd4 binds to GTPase-activating SPA-1, modulating its activity and subcellular localization." in: Molecular and cellular biology, Vol. 24, Issue 20, pp. 9059-69, (2004) (PubMed).: "Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression." in: Molecular and cellular biology, Vol. 15, Issue 1, pp. 552-60, (1995) (PubMed).
Aliases for SIPA1 抗体
signal-induced proliferation-associated 1 (SIPA1) 抗体Signal peptidase I (leader peptidase I) (sipA1) 抗体
signal-induced proliferation associated gene 1 (Sipa1) 抗体
signal-induced proliferation-associated 1 (Sipa1) 抗体
Spa1 抗体
SPA1 抗体
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