SIGLEC8 抗体
(Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM\\\\; MIM 603492) that mediates an association with SLAM-associated protein (SAP\\\\; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
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| SIGLEC8 抗体 | 人 | 兔 Polyclonal |
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| SIGLEC8 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| SIGLEC8 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| SIGLEC8 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| SIGLEC8 抗体 (AA 70-336) | 人 | 兔 Polyclonal |
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| SIGLEC8 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| SIGLEC8 抗体 (AA 18-122) | 人 | 小鼠 Monoclonal |
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| SIGLEC8 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| SIGLEC8 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| SIGLEC8 抗体 (AA 70-336) | 人 | 小鼠 Monoclonal |
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| SIGLEC8 抗体 (AA 70-336) | 人 | 小鼠 Monoclonal |
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| SIGLEC8 抗体 | 人 | Human Monoclonal |
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| SIGLEC8 抗体 (PerCP) | 人 | Human Monoclonal |
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| SIGLEC8 抗体 (PE) | 人 | Human Monoclonal |
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| SIGLEC8 抗体 (FITC) | 人 | Human Monoclonal |
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| Recombinant SIGLEC8 抗体 | 人 | Human Monoclonal |
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| SIGLEC8 抗体 (APC) | 人 | Human Monoclonal |
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| Recombinant SIGLEC8 抗体 | 人 | Human Monoclonal |
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| SIGLEC8 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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| SIGLEC8 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 94-122, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 373-406, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 70-336
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3H1
- 标记
- unconjugated
- 抗体亚型
- IgG2b kappa
- 抗原表位
- AA 18-122
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term, AA 93-122
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 373-406, C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- C1
- 标记
- unconjugated
- 抗体亚型
- IgG2a kappa
- 抗原表位
- AA 70-336
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- D1
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 70-336
Primary Antibody
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- ABS1401
- 标记
- PerCP
- 抗体亚型
- IgG1, kappa
Primary Antibody
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- ABS1401
- 标记
- FITC
- 抗体亚型
- IgG1, kappa
Primary Antibody
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- AK001
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- ABS1401
- 标记
- APC
- 抗体亚型
- IgG1, kappa
Primary Antibody
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- 1H10
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1
Latest Publications for our SIGLEC8 抗体
: "Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis." in: JCI insight, Vol. 4, Issue 19, (2019) (PubMed).
: "Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement." in: The Journal of allergy and clinical immunology, Vol. 121, Issue 2, pp. 499-505.e1, (2008) (PubMed).
: "Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies." in: The Journal of allergy and clinical immunology, Vol. 119, Issue 4, pp. 1005-11, (2007) (PubMed).
: "Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis." in: Blood, Vol. 101, Issue 12, pp. 5014-20, (2003) (PubMed).
: "Molecular characterization of a Siglec8 variant containing cytoplasmic tyrosine-based motifs, and mapping of the Siglec8 gene." in: Biochemical and biophysical research communications, Vol. 278, Issue 3, pp. 775-81, (2000) (PubMed).
: "Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily." in: The Journal of biological chemistry, Vol. 275, Issue 2, pp. 861-6, (2000) (PubMed).
: "Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils." in: The Journal of allergy and clinical immunology, Vol. 105, Issue 6 Pt 1, pp. 1093-100, (2000) (PubMed).
: "Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement." in: The Journal of allergy and clinical immunology, Vol. 121, Issue 2, pp. 499-505.e1, (2008) (PubMed).
: "Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies." in: The Journal of allergy and clinical immunology, Vol. 119, Issue 4, pp. 1005-11, (2007) (PubMed).
: "Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis." in: Blood, Vol. 101, Issue 12, pp. 5014-20, (2003) (PubMed).
: "Molecular characterization of a Siglec8 variant containing cytoplasmic tyrosine-based motifs, and mapping of the Siglec8 gene." in: Biochemical and biophysical research communications, Vol. 278, Issue 3, pp. 775-81, (2000) (PubMed).
: "Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily." in: The Journal of biological chemistry, Vol. 275, Issue 2, pp. 861-6, (2000) (PubMed).
: "Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils." in: The Journal of allergy and clinical immunology, Vol. 105, Issue 6 Pt 1, pp. 1093-100, (2000) (PubMed).
Aliases for SIGLEC8 抗体
sialic acid binding Ig like lectin 8 (SIGLEC8) 抗体sialic acid-binding Ig-like lectin 8 (LOC506364) 抗体
SAF2 抗体
SIGLEC-8 抗体
SIGLEC8 抗体
SIGLEC8L 抗体
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