SIAH1 抗体
(E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
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Latest Publications for our SIAH1 抗体
: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).: "Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6." in: PLoS ONE, Vol. 6, Issue 5, pp. e20389, (2011) (PubMed).
: "BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution." in: Journal of neurochemistry, Vol. 111, Issue 3, pp. 801-7, (2009) (PubMed).
: "A designer axially chiral amino sulfonamide as an efficient organocatalyst for direct asymmetric anti-selective Mannich reactions and syn-selective cross-aldol reactions." in: Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 15, Issue 27, pp. 6678-87, (2009) (PubMed).
: "Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor." in: Molecular and cellular biology, Vol. 28, Issue 14, pp. 4598-608, (2008) (PubMed).
: "Hypoxia-inducible factors in the first trimester human lung." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 55, Issue 4, pp. 355-63, (2007) (PubMed).
: "Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner." in: Oncogene, Vol. 23, Issue 45, pp. 7593-600, (2004) (PubMed).
: "Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling." in: Nature structural biology, Vol. 9, Issue 1, pp. 68-75, (2001) (PubMed).
: "Siah-1 binds and regulates the function of Numb." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 26, pp. 15067-72, (2001) (PubMed).
: "The function(s) of CAK, the p34cdc2-activating kinase." in: Trends in biochemical sciences, Vol. 19, Issue 11, pp. 496-500, (1995) (PubMed).
Aliases for SIAH1 抗体
E3 ubiquitin-protein ligase Siah1 (Tsp_03055) 抗体E3 ubiquitin-protein ligase siah-1 (siah-1) 抗体
siah E3 ubiquitin protein ligase 1 (Siah1) 抗体
siah E3 ubiquitin protein ligase 1 (siah1) 抗体
siah E3 ubiquitin protein ligase 1 (SIAH1) 抗体
siah E3 ubiquitin protein ligase 1 L homeolog (siah1.L) 抗体
id:ibd2635 抗体
SIAH 抗体
siah 抗体
Siah1 抗体
Siah1a 抗体
SIAH1A 抗体
zgc:56026 抗体
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