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小鼠 anti-人 IgE Antibody (FITC)

FACS Monoclonal 4H10 IgG1 FITC
产品编号 ABIN614234
发货至: 中国
  • 抗原 See all IgE products
    IgE
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    FITC
    应用范围
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    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human
    克隆位点
    4H10
    亚型
    IgG1
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Excitation/Emission wavelength: 494 nm/514 nm

    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Product is photosensitive and should be protected from light.
  • 抗原
    IgE
    Abstract
    IgE 产品
    背景
    Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.Synonyms: Immunoglobulin E human
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