anti-人 TEK 抗体 for Enzyme Immunoassay

Recommended TEK Antibody

抗原
TEK Tyrosine Kinase, Endothelial (TEK) 抗体
  • TEK
  • DKFZp469E064
  • AA517024
  • Cd202b
  • Hyk
  • Tie2
  • tie-2
  • CD202B
  • TIE-2
  • TIE2
  • VMCM
  • VMCM1
  • Tie-2
  • tie2
  • TEK receptor tyrosine kinase
  • angiopoietin-1 receptor
  • TEK tyrosine kinase, endothelial
  • TEK
  • LOC100408334
  • tek
  • Tek
抗原表位
pTyr1113
28
25
22
20
15
15
11
10
10
8
8
8
6
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用

287
163
100
9
8
宿主

235
64
10
3
2
1
克隆类型
多克隆
标记
This TEK antibody is un-conjugated
21
14
10
8
8
8
8
8
8
7
6
4
4
4
4
4
4
1
应用范围
Enzyme Immunoassay (EIA)
173
128
69
53
48
22
21
19
16
12
7
6
6
3
选项

Available images

产品编号 ABIN358489
$ 484.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN155164 EIA FACS WB Biotin Mouse IgG1 Extracellular Domain Cl-9 3
1 ABIN155163 EIA FACS WB Biotin Mouse IgG1 Extracellular Domain Cl-2 3
1 ABIN155165 EIA FACS WB Biotin Mouse IgG1 Cl-16 4
1 ABIN115157 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Cl-9 4
1 ABIN115155 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Cl-2 4
1 ABIN115159 EIA FACS IHC (fro) WB Mouse IgG1 Extracellular Domain Cl-16 4
1 ABIN5552253 EIA IHC (p) WB Rabbit Ig Fraction C-Term Polyclonal 0

General

抗原 TEK Tyrosine Kinase, Endothelial (TEK) 抗体
抗原表位 pTyr1113
(28), (25), (22), (20), (15), (15), (11), (10), (10), (8), (8), (8), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用
(287), (163), (100), (9), (8)
宿主
(235), (64), (10), (3), (2), (1)
克隆类型
多克隆
标记 This TEK antibody is un-conjugated
(21), (14), (10), (8), (8), (8), (8), (8), (8), (7), (6), (4), (4), (4), (4), (4), (4), (1)
应用范围 Enzyme Immunoassay (EIA)
(173), (128), (69), (53), (48), (22), (21), (19), (16), (12), (7), (6), (6), (3)
Pubmed 5个引用可参考
Supplier

TEK抗体详情

TEK目标详情 使用细节 贮存及处理 References for anti-TEK antibody (ABIN358489) 图像
特异性 This antibody detects TEK pTyr1113. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
纯化方法 Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
免疫原 This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK.
亚型 Ig Fraction
Plasmids, Primers & others

TEK目标详情

TEK抗体详情 使用细节 贮存及处理 References for anti-TEK antibody (ABIN358489) 图像 回页首
抗原
别名 CD202b / TEK (TEK Antibody 摘要)
背景 The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
分子量 125810 Da
基因ID 83659, 9606
UniProt Q02763
途径 RTK signaling, Growth Factor Binding

使用细节

TEK抗体详情 TEK目标详情 贮存及处理 References for anti-TEK antibody (ABIN358489) 图像 回页首
应用备注 ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

TEK抗体详情 TEK目标详情 使用细节 References for anti-TEK antibody (ABIN358489) 图像 回页首
状态 Liquid
浓度 0.25 mg/mL
缓冲液 PBS with 0.09 % (W/V) Sodium Azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-TEK antibody (ABIN358489)

TEK抗体详情 TEK目标详情 使用细节 贮存及处理 图像 回页首
背景

Cascone, Audero, Giraudo, Napione, Maniero, Philips, Collard, Serini, Bussolino: "Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1." in: Blood, Vol. 102, Issue 7, pp. 2482-90, 2003

DeBusk, Chen, Nishishita, Chen, Thomas, Lin: "Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis." in: Arthritis and rheumatism, Vol. 48, Issue 9, pp. 2461-71, 2003

Poncet, Gasc, Janzer, Meyer, Juillerat-Jeanneret: "Expression of Tie-2 in human peripheral and autonomic nervous system." in: Neuropathology and applied neurobiology, Vol. 29, Issue 4, pp. 361-9, 2003

Lee, Koh: "Shear stress activates Tie2 receptor tyrosine kinase in human endothelial cells." in: Biochemical and biophysical research communications, Vol. 304, Issue 2, pp. 399-404, 2003

Sussman, Upalakalin, Roberts, Kocher, Benjamin: "Blood markers for vasculogenesis increase with tumor progression in patients with breast carcinoma." in: Cancer biology & therapy, Vol. 2, Issue 3, pp. 255-6, 2003

图像

TEK抗体详情 TEK目标详情 使用细节 贮存及处理 References for anti-TEK antibody (ABIN358489) 回页首
厂商提供的图像
 image for anti-TEK Tyrosine Kinase, Endothelial (TEK) (pTyr1113) antibody (ABIN358489) anti-TEK Tyrosine Kinase, Endothelial (TEK) (pTyr1113) antibody