anti-大鼠 Ret Proto-Oncogene 抗体 for Western Blotting

Recommended Ret Proto-Oncogene Antibody (supplied by: Log in to see )

抗原
Ret Proto-Oncogene (RET) 抗体
  • c-ret
  • cret
  • etID315074.13
  • ret1
  • wu:fd13h01
  • X-ret
  • ret-A
  • xret
  • RET
  • MTC1
  • CDHF12
  • CDHR16
  • HSCR1
  • MEN2A
  • MEN2B
  • PTC
  • RET-ELE1
  • RET51
  • RET9
  • c-Ret
  • ret proto-oncogene receptor tyrosine kinase
  • ret proto-oncogene S homeolog
  • ret proto-oncogene
  • ret
  • ret.S
  • RET
  • Ret
抗原表位
pTyr1096
49
42
26
26
26
22
18
15
14
11
11
8
7
7
7
7
7
7
7
6
5
5
4
4
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
362
128
118
9
3
2
2
2
2
1
1
1
1
1
1
1
宿主

256
104
5
2
1
1
克隆类型
多克隆
标记
This Ret Proto-Oncogene antibody is un-conjugated
16
14
14
12
9
9
6
6
6
6
6
5
5
5
5
5
5
1
1
1
1
1
应用范围
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
270
155
122
67
65
39
34
12
7
6
6
3
3
1
1
Supplier
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产品编号 ABIN6271278
$ 450.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
16.802607 ABIN6271568 ELISA ICC IF IHC WB Rabbit IgG pTyr1015 Log in to see Polyclonal 0
16.55833 ABIN3186735 ELISA WB Rabbit IgG Thr788 Log in to see Polyclonal 0
16.55833 ABIN3186734 ELISA IF IHC WB Rabbit IgG Thr77 Log in to see Polyclonal 0
12.755724 ABIN3182407 ELISA IHC WB Rabbit IgG pTyr1062 Log in to see Polyclonal 0
12.755724 ABIN3182216 ELISA WB Rabbit IgG pTyr1015 Log in to see Polyclonal 0
12.755724 ABIN2150513 ELISA WB Rabbit IgG pTyr1062 Log in to see Polyclonal 0
10.802607 ABIN2705182 IC IF IHC WB Rabbit C-Term, pTyr1062 Log in to see Polyclonal 0
10.802607 ABIN2705184 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal 0
10.802607 ABIN6256615 ELISA ICC IF WB Rabbit IgG pTyr1062 Log in to see Polyclonal 0
10.802607 ABIN6264702 ELISA ICC IF WB Rabbit IgG Log in to see Polyclonal 0
10.802607 ABIN2972091 IF/ICC IHC WB KLH Rabbit IgG C-Term, pTyr1062 Log in to see Polyclonal 0
10.802607 ABIN2972089 IF/ICC IHC WB Rabbit C-Term Log in to see Polyclonal 0
7.8026066 ABIN2777172 WB Rabbit C-Term Log in to see Polyclonal 0
7.8026066 ABIN6271276 ELISA ICC IF WB Rabbit IgG pTyr905 Log in to see Polyclonal 0
7 ABIN680788 IF (p) IHC (p) WB Rabbit IgG AA 998-1030 Log in to see Polyclonal 0
7 ABIN745523 IF (p) IHC (p) WB Rabbit IgG pTyr905 Log in to see Polyclonal 0
4.8026066 ABIN1531387 ELISA WB Rabbit IgG AA 991-1040, pTyr1015 Log in to see Polyclonal 2
4.8026066 ABIN1531965 ELISA WB Rabbit IgG AA 1041-1090, pTyr1062 Log in to see Polyclonal 0
4.8026066 ABIN1532999 ELISA WB Rabbit IgG AA 1041-1090 Log in to see Polyclonal 0
4.8026066 ABIN2559573 WB Rabbit IgG AA 530-565 Log in to see Polyclonal 0

General

抗原 Ret Proto-Oncogene (RET) 抗体
抗原表位 pTyr1096
(49), (42), (26), (26), (26), (22), (18), (15), (14), (11), (11), (8), (7), (7), (7), (7), (7), (7), (7), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(362), (128), (118), (9), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
宿主
(256), (104), (5), (2), (1), (1)
克隆类型
多克隆
标记 This Ret Proto-Oncogene antibody is un-conjugated
(16), (14), (14), (12), (9), (9), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (1), (1), (1), (1), (1)
应用范围 ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(270), (155), (122), (67), (65), (39), (34), (12), (7), (6), (6), (3), (3), (1), (1)
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Ret Proto-Oncogene抗体详情

Ret Proto-Oncogene目标详情 使用细节 贮存及处理 图像
特异性 Ret (Phospho-Tyr1096) Antibody detects endogenous levels of Ret only when phosphorylated at Tyr1096
交叉反应 人, 小鼠, 大鼠
纯化方法 The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
免疫原 A synthesized peptide derived from human Ret (Phospho-Tyr1096)
亚型 IgG
Plasmids, Primers & others

Ret Proto-Oncogene目标详情

Ret Proto-Oncogene抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 Ret (RET Antibody 摘要)
背景

Description: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. Phosphorylates PTK2/FAK1. Regulates both cell death/survival balance and positional information. Required for the molecular mechanisms orchestration during intestine organogenesis, involved in the development of enteric nervous system and renal organogenesis during embryonic life, and promotes the formation of Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an integrin (e.g. ITGB1 and ITGB3)-dependent manner. Involved in the development of the neural crest. Active in the absence of ligand, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage. Acts as a dependence receptor, in the presence of the ligand GDNF in somatotrophs (within pituitary), promotes survival and down regulates growth hormone (GH) production, but triggers apoptosis in absence of GDNF. Regulates nociceptor survival and size. Triggers the differentiation of rapidly adapting (RA) mechanoreceptors. Mediator of several diseases such as neuroendocrine cancers, these diseases are characterized by aberrant integrins-regulated cell migration. Mediates, through interaction with GDF15-receptor GFRAL, GDF15-induced cell-signaling in the brainstem which induces inhibition of food-intake. Activates MAPK- and AKT-signaling pathways (PubMed:28846097, PubMed:28953886, PubMed:28846099). Isoform 1 in complex with GFRAL induces higher activation of MAPK-signaling pathway than isoform 2 in complex with GFRAL (PubMed:28846099).

Gene: RET

分子量 175kDa
基因ID 5979
UniProt P07949
途径 RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation

使用细节

Ret Proto-Oncogene抗体详情 Ret Proto-Oncogene目标详情 贮存及处理 图像 回页首
应用备注 WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
限制 仅限研究用

贮存及处理

Ret Proto-Oncogene抗体详情 Ret Proto-Oncogene目标详情 使用细节 图像 回页首
状态 Liquid
浓度 1 mg/mL
缓冲液 Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at -20 °C.Stable for 12 months from date of receipt
有效期 12 months

图像

Ret Proto-Oncogene抗体详情 Ret Proto-Oncogene目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 at 1/200 staining Human kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 at 1/200 staining Mouse kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 at 1/200 staining Rat kidney tissue sections by IHC-P. The tissue was for...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeab...
Western Blotting (WB) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) Western blot analysis of Ret (Phospho-Tyr1096) using EGF treated HepG2 whole cell lys...