Ret Proto-Oncogene 产品
(Ret Proto-Oncogene (RET))
Categories
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008].
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Featured Ret Proto-Oncogene Categories
Ret Proto-Oncogene 抗体
High quality antibodies with extensive validation data.
Ret Proto-Oncogene ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Ret Proto-Oncogene 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ret Proto-Oncogene 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (5)
Cat. No.
ABIN6940507
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (4)
Cat. No.
ABIN519735
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, Coat
Validations
- (4)
Cat. No.
ABIN6940506
Quantity
100 μg
Datasheet
Datasheet
Recommended Ret Proto-Oncogene ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969912
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730509
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385661
Quantity
96 tests
Datasheet
Datasheet
Recommended Ret Proto-Oncogene 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570106
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570105
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570104
Quantity
5 μg
Datasheet
Datasheet
Latest Publications for our Ret Proto-Oncogene Products
: "Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo." in: Biomaterials, Vol. 88, pp. 1-11, (2016) (PubMed).: "Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence." in: Nature, Vol. 535, Issue 7612, pp. 440-3, (2016) (PubMed).
: "Prognostic and Predictive Values of Subcellular Localisation of RET in Renal Clear-Cell Carcinoma." in: Disease markers, Vol. 2016, pp. 6870470, (2016) (PubMed).
: "Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation." in: BMC biology, Vol. 13, pp. 24, (2015) (PubMed).
: "The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function." in: Nature, Vol. 514, Issue 7520, pp. 98-101, (2014) (PubMed).
: "RET is a potential tumor suppressor gene in colorectal cancer." in: Oncogene, Vol. 32, Issue 16, pp. 2037-47, (2013) (PubMed).
: "Site-specific gene expression and localization of growth factor ligand receptors RET, GFRα1 and GFRα2 in human adult colon." in: Cell and tissue research, Vol. 354, Issue 2, pp. 371-80, (2013) (PubMed).
: "Profiling post-centrifugation delay of serum and plasma with antibody bead arrays." in: Journal of proteomics, Vol. 95, pp. 46-54, (2013) (PubMed).
: "Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth." in: Cell research, Vol. 21, Issue 2, pp. 327-37, (2011) (PubMed).
: "Glial cell line-derived neurotrophic factor and endothelial cells promote self-renewal of rabbit germ cells with spermatogonial stem cell properties." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 8, pp. 2604-14, (2011) (PubMed).
Synonyms and alternative names related to Ret Proto-Oncogene
ret proto-oncogene receptor tyrosine kinase (ret), ret proto-oncogene S homeolog (ret.S), ret proto-oncogene (RET), ret proto-oncogene (ret), ret proto-oncogene (Ret), c-ret, c-Ret, CDHF12, CDHR16, cret, etID315074.13, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET, ret-A, RET-ELE1, ret1, RET9, RET51, wu:fd13h01, X-ret, xretProtein level used designations for Ret Proto-Oncogene
- proto-oncogene tyrosine-protein kinase receptor Ret
- receptor tyrosine kinase
- ret proto-oncogene
- tryptase
- proto-oncogene tyrosine-protein kinase receptor Ret-like
- RET transforming sequence
- cadherin family member 12
- cadherin-related family member 16
- hydroxyaryl-protein kinase
- proto-oncogene c-Ret
- ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
- Ret gene for receptor tyrosin
- Ret proto-oncogene (multiple endocrine neoplasia MEN2A MEN2B and medullary thyroid carcinoma 1 Hirschsprung disease)
- ret tyrosine kinase
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