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Mouse (Murine) PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413709
Hamada, Gonda, Takeda, Sato, Watanabe, Yambe, Satomi, Ohuchi: In vivo imaging of the molecular distribution of the VEGF receptor during angiogenesis in a mouse model of ischemia. in Blood 2011
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413706
Tsuchida, Schneider, Pizani, Oliveira: Lead and aluminum bonding in Pb-AI metaphosphate glasses. in Inorganic chemistry 2008
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN804609
Huang, Zhao, Fields, Ransohoff, Zhou: Imatinib attenuates skeletal muscle dystrophy in mdx mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN1589629
Rezzola, Dal Monte, Belleri, Bugatti, Chiodelli, Corsini, Cammalleri, Cancarini, Morbidelli, Oreste, Bagnoli, Semeraro, Presta: Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy. in Diabetes 2015
PDGF-B (显示 PDGFB 蛋白) expression was found in ovarian tumor microvessels in 72% of cases. High expression of PDGF (显示 PDGFA 蛋白) in pericapillary cells was strongly associated with high expression of this marker in cancer cells. Significant correlations between PDGF-B (显示 PDGFB 蛋白) and nestin (显示 NES 蛋白) expression in malignant tumor microvessels were also found.
SOX7 transcription factor (显示 SOX7 蛋白) mediates PDGF (显示 PDGFA 蛋白)-BB-induced IL-33 (显示 IL33 蛋白) expression.
High expression of PDGF (显示 PDGFA 蛋白)-BB may be involved in the pathogenesis of Graves' disease. CCR2 (显示 CCR2 蛋白)-positive macrophages may induce the expression of PDGF (显示 PDGFA 蛋白)-BB through HIF-1alpha (显示 HIF1A 蛋白) signal.
rhPDGF-BB promoted the proliferation of hADSCs via miR (显示 MLXIP 蛋白)-363/PI3K (显示 PIK3CA 蛋白)/Akt (显示 AKT1 蛋白) pathway, indicating that rhPDGF-BB combined with ADSCs could treat Achilles tendinitis via miR (显示 MLXIP 蛋白)-363/PI3K (显示 PIK3CA 蛋白)/Akt (显示 AKT1 蛋白) pathway.
This review showed that PDGFB was one of the common gene involved included with brain calcification.
Rare Skin Tumor Dermatofibrosarcoma Protuberans (DFSP) is characterized by the translocation of the PDGFB (显示 PDGFB 蛋白) gene to the collagen 1A1 (显示 COL1A1 蛋白) gene.
Transglutaminase type 2 affects cell migration through post-translational modification of PDGF (显示 PDGFA 蛋白)-BB.
PDGF-B (显示 PDGFB 蛋白) rs1800818 polymorphism might play a role in mediating the susceptibility to severe fever with thrombocytopenia syndrome in Chinese individuals.
PDAP-1 (显示 PDAP1 蛋白) as an effecter of PDGF (显示 PDGFA 蛋白) signaling in glioma cells
High PDGFB expression is associated with gastric cancer.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
PDGF subunit B
, PDGF, B chain
, platelet-derived growth factor 2
, platelet-derived growth factor B chain
, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
, platelet-derived growth factor subunit B
, platelet-derived growth factor, beta polypeptide (oncogene SIS)
, proto-oncogene c-Sis