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Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN1589629
Rezzola, Dal Monte, Belleri, Bugatti, Chiodelli, Corsini, Cammalleri, Cancarini, Morbidelli, Oreste, Bagnoli, Semeraro, Presta: Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy. in Diabetes 2015
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN1590225
Lim, Moon, Shin, Kim, Cho, Kim, Park, Choi, Ko, Chung, Lee, Jang, Kim, Park: Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats. in Cardiovascular research 2011
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413706
Tsuchida, Schneider, Pizani, Oliveira: Lead and aluminum bonding in Pb-AI metaphosphate glasses. in Inorganic chemistry 2008
Mouse (Murine) PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413709
Hamada, Gonda, Takeda, Sato, Watanabe, Yambe, Satomi, Ohuchi: In vivo imaging of the molecular distribution of the VEGF receptor during angiogenesis in a mouse model of ischemia. in Blood 2011
Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN804609
Huang, Zhao, Fields, Ransohoff, Zhou: Imatinib attenuates skeletal muscle dystrophy in mdx mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009
This review showed that PDGFB was one of the common gene involved included with brain calcification.
Rare Skin Tumor Dermatofibrosarcoma Protuberans (DFSP) is characterized by the translocation of the PDGFB (显示 PDGFB 蛋白) gene to the collagen 1A1 (显示 COL1A1 蛋白) gene.
Transglutaminase type 2 affects cell migration through post-translational modification of PDGF (显示 PDGFA 蛋白)-BB.
PDGF-B (显示 PDGFB 蛋白) rs1800818 polymorphism might play a role in mediating the susceptibility to severe fever with thrombocytopenia syndrome in Chinese individuals.
PDAP-1 (显示 PDAP1 蛋白) as an effecter of PDGF (显示 PDGFA 蛋白) signaling in glioma cells
High PDGFB expression is associated with gastric cancer.
We observed that regenerating and necrotic muscle fibers in muscle biopsy samples from Duchenne muscular dystrophy (显示 DMD 蛋白) patients expressed PDGF (显示 PDGFA 蛋白)-BB.
Elevated PDGFB (显示 PDGFB 蛋白) expression was noted in 29% of patients with papillary renal cell carcinoma (显示 MOK 蛋白).
Insulin (显示 INS 蛋白) treatment caused sustained Akt (显示 AKT1 蛋白) activity, whereas EGF (显示 EGF 蛋白) or PDGF (显示 PDGFA 蛋白)-AA promoted transient signaling; PDGF (显示 PDGFA 蛋白)-BB produced sustained responses at higher concentrations.Transient responses to EGF (显示 EGF 蛋白) were caused by negative feedback at the receptor level, as a second treatment yielded minimal responses, whereas parallel exposure to IGF-I (显示 IGF1 蛋白) caused full Akt (显示 AKT1 蛋白) activation
high-throughput affinity plasma proteomic profiling is a valuable research strategy to identify potential candidate biomarkers for thrombosis-related disorders, and our study suggests a novel association of PDGFB plasma levels with venous thromboembolism.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
PDGF subunit B
, PDGF, B chain
, platelet-derived growth factor 2
, platelet-derived growth factor B chain
, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
, platelet-derived growth factor subunit B
, platelet-derived growth factor, beta polypeptide (oncogene SIS)
, proto-oncogene c-Sis