anti-MET (MET) 抗体产品概述

Full name:: anti-Met Proto-Oncogene 抗体 (MET)

在www.antibodies-online.cn可供762 Met Proto-Oncogene (MET) 抗体的32不同的供货商。再加上，我们可以发MET 蛋白 (64) 和 MET 试剂盒 (61)和数多这个蛋白质的别的产品。总共913 MET产品已列进来了。

别名:: AI838057, AUTS9, c-met, HGF, Hgfr, Par4, RCCP2

列出全部抗体	基因	基因ID	UniProt
	MET	4233	P08581
	MET	17295
	MET	24553	P97523
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引用最多的anti-MET 抗体

Human Polyclonal MET Primary Antibody for BR, CyTOF - ABIN5012912 : Skibinski, Elborn, Ennis: Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor. in American journal of physiology. Lung cellular and molecular physiology 2007 (PubMed)
Show all 14 Pubmed References
Human Polyclonal MET Primary Antibody for IHC - ABIN966572 : Fan, Ma, Gao, Yuan, Meng, Goldberg, Rosen: The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair. in Molecular and cellular biology 2001 (PubMed)
Show all 5 Pubmed References
Human Monoclonal MET Primary Antibody for FACS - ABIN4896926 : Tervonen, Belitškin, Pant, Englund, Marques, Ala-Hongisto, Nevalaita, Sihto, Heikkilä, Leidenius, Hewitson, Ramachandra, Moilanen, Joensuu, Kovanen, Poso, Klefström: Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. in Oncogene 2016 (PubMed)
Show all 5 Pubmed References
Human Polyclonal MET Primary Antibody for ELISA (Detection), FACS - ABIN4899934 : Coxon, Rex, Meyer, Sun, Sun, Chen, Radinsky, Kendall, Burgess: Soluble c-Met receptors inhibit phosphorylation of c-Met and growth of hepatocyte growth factor: c-Met-dependent tumors in animal models. in Molecular cancer therapeutics 2011 (PubMed)
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Human Polyclonal MET Primary Antibody for CyTOF, FACS - ABIN4900630 : Phillip, Zaman, Shentu, Balakrishnan, Zhang, Baladandayuthapani, Taverna, Redkar, Wang, Stellrecht, Gandhi: Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines. in Journal of hematology & oncology 2013 (PubMed)
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Human Polyclonal MET Primary Antibody for WB - ABIN1881539 : Holgren, Dougherty, Edwin, Cerasi, Taylor, Fichera, Joseph, Bissonnette, Khare: Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: sprouty/c-Met upregulation in human colonic adenocarcinomas. in Oncogene 2010 (PubMed)
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Human MET Primary Antibody for IHC - ABIN966569 : Gherardi, Youles, Miguel, Blundell, Iamele, Gough, Bandyopadhyay, Hartmann, Butler: Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
Show all 4 Pubmed References
Human Polyclonal MET Primary Antibody for IHC - ABIN966571 : Shiu, Bleecker: Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
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Human MET Primary Antibody for IHC - ABIN966570 : Schiering, Knapp, Marconi, Flocco, Cui, Perego, Rusconi, Cristiani: Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
Show all 4 Pubmed References
Human Polyclonal MET Primary Antibody for FACS, IF (p) - ABIN671661 : Gao, Bing, Li, Yang, Li, Chen: Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma. in Medical oncology (Northwood, London, England) 2013 (PubMed)
Show all 4 Pubmed References

更多抗MET的相互作用对抗体

Human Met Proto-Oncogene (MET) interaction partners

these findings highlight the relevance of cross-species protein interactions between murine feeder cells and human epithelial cells in 3T3-J2 co-culture and demonstrate that STAT6 (显示 STAT6 抗体) phosphorylation occurs in response to MET activation in epithelial cells. However, STAT6 (显示 STAT6 抗体) nuclear translocation does not occur in response to HGF (显示 HGF 抗体), precluding the transcriptional activity of STAT6 (显示 STAT6 抗体).
c-Met-activated Mesenchymal Stem Cells (MSC (显示 MSC 抗体)) pre-exposed to hypoxia interact with PrPC (显示 PRNP 抗体) at the site of ischemic injury to increase the efficiency of MSC (显示 MSC 抗体) transplantation.
This study demonstrates that simultaneous inhibition of c-Met and Src (显示 SRC 抗体) signaling in MD-MSCs triggers apoptosis and reveals vulnerable pathways that could be exploited to develop NF2 (显示 NF2 抗体) therapies.
prolonged treatment of single HGF/c-Met or Hh inhibitor leads to resistance to these single inhibitors, likely because the single c-Met treatment leads to enhanced expression of Shh (显示 SHH 抗体), and vice versa. Targeting both the HGF/c-Met and Hh pathways simultaneously overcame the resistance to the single-inhibitor treatment and led to a more potent antitumor effect in combination with the chemotherapy treatment.
We identified unique and tumor-specific tyrosine phosphorylation rewiring in tumors resistant to treatment with the irreversible third-generation EGFR (显示 EGFR 抗体)-inhibitor, osimertinib, or the novel dual-targeting EGFR (显示 EGFR 抗体)/Met antibody, JNJ-61186372.
TGF-beta (显示 TGFB1 抗体) negatively controls the HGF/c-MET pathway by regulating of stemness in glioblastoma.
the results of real-time PCR and western blotting revealed that Huaier extract decreased p65 and c-Met expression and increased IkappaBalpha expression, while paclitaxel increased p65 expression and reduced IkappaBalpha and c-Met expression.The molecular mechanisms may be involved in the inhibition of the NF-kappaB pathway and c-Met expression
Data found that the expression of c-Met was significantly increased in human oral squamous cell carcinoma (OSCC) tissues than in normal mucosa adjacent to the tumor, but was not correlated with clinicopathological parameters. Also, further findings indicated the potential role of c-Met in the progression of OSCC.
Our data show that S49076 exerts its cytotoxic activity at low doses on MET-dependent cells through MET inhibition, whereas it inhibits growth of MET-independent cells at higher but clinically relevant doses by targeting Aurora B (显示 AURKB 抗体)
In SCCHN, immunohistochemical overexpression of c-MET above cut-off levels III and particularly II was associated with inferior survival outcomes and advanced disease

Mouse (Murine) Met Proto-Oncogene (MET) interaction partners

PAR-4 (显示 F2RL3 抗体) is expressed in cardiac fibroblasts and is regulated by extracellular glucose and in diabetes mellitus.
prolonged treatment of single HGF/c-Met or Hh inhibitor leads to resistance to these single inhibitors, likely because the single c-Met treatment leads to enhanced expression of Shh (显示 SHH 抗体), and vice versa. Targeting both the HGF/c-Met and Hh pathways simultaneously overcame the resistance to the single-inhibitor treatment and led to a more potent antitumor effect in combination with the chemotherapy treatment.
SOCS1 (显示 SOCS1 抗体) attenuates migration and invasion properties of hepatocellular carcinoma cells at least partly via modulation of MET-mediated epithelial-mesenchymal transition, and controls invasive tumor growth.
Met has a role in promoting formation of double minute chromosomes induced by Sei-1 (显示 SERTAD1 抗体) in NIH-3T3 murine fibroblasts
Genetic activation of the antioxidant transcription factor Nrf2 improves liver damage and repair in hepatocyte-specific c-met-deficient mice mainly through restoring a balance in the cellular redox homeostasis.
MET promoted the development of squamous tumors by stimulating the synthesis and release of ligands that activate the epidermal growth factor receptor (EGFR (显示 EGFR 抗体)).
through the activation of EGFR, MET activation parallels a RAS pathway to contribute to human and mouse cutaneous cancers.
Results show that c-MET expression is significantly low in pancreatic neuroendocrine tumors (PNETs) and is under the regulation of Meg3-mediated transcriptional and epigenetic mechanisms which contributes to the pathogenesis of PNETs.
Findings indicate a role for the hepatocyte growth factor receptor HGFR/c-MET pathway in neutrophil recruitment and function and suggest that c-MET inhibitor co-treatment may improve responses to cancer immunotherapy in settings beyond c-MET-dependent tumors.
Results demonstrate a new mechanism for the modulation of synapse formation, whereby MET activation induces an alignment of presynaptic and postsynaptic elements that are necessary for assembly and formation of functional synapses by subsets of neocortical neurons that express MET/beta-catenin (显示 CTNNB1 抗体) complex.

Cow (Bovine) Met Proto-Oncogene (MET) interaction partners

possible cooperative role of the EGF (显示 EGF 抗体) and HGF (显示 HGF 抗体) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow

MET 抗原简介

Antigen Summary

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MET

MET proto-oncogene, receptor tyrosine kinase (MET) 抗体
met proto-oncogene (Met) 抗体
MET proto-oncogene, receptor tyrosine kinase (Met) 抗体

AI838057 抗体
AUTS9 抗体
c-met 抗体
HGF 抗体
Hgfr 抗体
Par4 抗体
RCCP2 抗体

Protein level used designations for anti-Met Proto-Oncogene (MET) 抗体

HGF receptor , HGF/SF receptor , SF receptor , hepatocyte growth factor receptor , met proto-oncogene tyrosine kinase , proto-oncogene c-Met , scatter factor receptor , tyrosine-protein kinase Met , c-Met , HGF receptor c-Met

GENE ID	SPECIES
4233	Homo sapiens
17295	Mus musculus
24553	Rattus norvegicus
403438	Canis lupus familiaris
280855	Bos taurus
654328	Sus scrofa
100126565	Oryctolagus cuniculus

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