Survival of Motor Neuron 2, Centromeric ELISA Kit

5 products by 4 suppliers: Abbexa | Biomatik | Cloud-Clone | DLDEVELOP
View Product
SMN2 ELISA Kit
$589.47
96 tests
Human
Recommendations are based on data provided indicating:
  • ELISA Kit Sensitivity
    The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
  • ELISA Kit Specificity
    The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
  • Experiment Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
  • ELISA Kit Robustness
    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
Picking recommended ELISA Kits will save you time - yet all 5 products covered by our Money Back Guarantee!
Relevance Score uniqeid Catalogue Id Detection Method Sample Type Analytical Method Detection Range Sensitivity Supplier References Quantity Price
7.5 element-ABIN419178 ABIN419178 Colorimetric
(Pre-coated)
Tissue Homogenate Quantitative Sandwich ELISA 0.15 ng/mL - 10 ng/mL 0.058 ng/mL Log in to see
  • (1)
96 tests $589.47
7.5 element-ABIN1572452 ABIN1572452 Colorimetric
(Pre-coated)
Tissue Homogenate Quantitative Sandwich ELISA 0.156 ng/mL - 10 ng/mL 0.058 ng/mL Log in to see
  • (1)
96 tests $908.41
6 element-ABIN5659041 ABIN5659041 Colorimetric
(Pre-coated)
Tissue Homogenate Quantitative Sandwich ELISA 0.156 ng/mL - 10 ng/mL 0.058 ng/mL Log in to see
96 tests $971.15
5 element-ABIN2539310 ABIN2539310 Colorimetric
(Pre-coated)
Tissue Homogenate Sandwich ELISA 0.156-10 ng/mL 0.058 ng/mL Log in to see
96 tests $838.60
5 element-ABIN4972873 ABIN4972873 Colorimetric
(Pre-coated)
Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate Sandwich ELISA 0.156-10 ng/mL < 0.058 ng/mL Log in to see
96 tests $760.42

SMN2 Antigen Profile

Antigen Summary

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. While mutations in the telomeric copy are associated with spinal muscular atrophy, mutations in this gene, the centromeric copy, do not lead to disease. This gene may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7, which is thought to be an exon splice enhancer. Note that the nine exons of both the telomeric and centromeric copies are designated historically as exon 1, 2a, 2b, and 3-8. It is thought that gene conversion events may involve the two genes, leading to varying copy numbers of each gene. The full length protein encoded by this gene localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. Four transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with SMN2

  • survival of motor neuron 2, centromeric (SMN2) ELISA Kit
  • survival motor neuron protein (LOC461829) ELISA Kit
  • BCD541 ELISA Kit
  • C-BCD541 ELISA Kit
  • GEMIN1 ELISA Kit
  • SMNC ELISA Kit
  • TDRD16B ELISA Kit
  • SMN2 ELISA Kit

Protein level used designations for SMN2

component of gems 1 , gemin-1 , survival motor neuron protein , tudor domain containing 16B , survival of motor neuron 2, centromeric

GENE ID SPECIES
6607 Homo sapiens
461829 Pan troglodytes
您还需要查找其他产品吗?