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SMURF2 ELISA试剂盒

(SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3. In this way, SMAD2 may recruit substrates, such as SNON, for ubiquitin-mediated degradation. Enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2. Coexpression of SMURF2 with SMAD1 results in considerable decrease in steady-state level of SMAD1 protein and a smaller decrease of SMAD2 level (By similarity).
SMURF2 ELISA 试剂盒 SMURF2 ELISA 试剂盒 SMURF2 ELISA 试剂盒 (ABIN6970246)

SMURF2 适用: 人 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

SMURF2 ELISA 试剂盒 SMURF2 ELISA 试剂盒 SMURF2 ELISA 试剂盒 (ABIN6959517)

SMURF2 适用: 大鼠 Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Cell Lysate, Tissue Homogenate

SMURF2 ELISA 试剂盒 (ABIN1131328)

SMURF2 适用: 小鼠 Colorimetric

SMURF2 ELISA试剂盒 by 适用

Find SMURF2 ELISA试剂盒 for a variety of species such as anti-Human SMURF2, anti-Mouse SMURF2, anti-Rat SMURF2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular SMURF2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970246
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959517
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1131328
Quantity 96 tests
Datasheet Datasheet

Aliases for SMURF2 ELISA试剂盒

SMAD specific E3 ubiquitin protein ligase 2 (SMURF2) ELISA试剂盒
SMAD specific E3 ubiquitin protein ligase 2 (smurf2) ELISA试剂盒
SMAD specific E3 ubiquitin protein ligase 2 (Smurf2) ELISA试剂盒
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