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抗Human ECD 抗体:
抗Mouse (Murine) ECD 抗体:
抗Goat ECD 抗体:
The interaction of ECD with RUVBL1, and its CK2-mediated phosphorylation, independent of its interaction with PIH1D1, are important for its cell cycle regulatory function.
Ecdysoneless and H-Ras expressing human mammary epithelial cells form tumors in NOD/SCID mice.
TXNIP has a role in the pathway involving hEcd to increase p53 stability and activity
Ecd is a novel tumor-promoting factor that is differentially expressed in pancreatic cancer and potentially regulates glucose metabolism within cancer cells.
Ecd as a novel marker for breast cancer progression and show that levels of Ecd expression predict poorer survival in Her2/neu overexpressing breast cancer patients.
Ecd localizes to both nucleus & cytoplasm & shuttles between the nucleus and cytoplasm; however, it exhibits strong nuclear export. Based on previous yeast studies & evidence provided here, we suggest that Ecd functions as a transcriptional regulator.
The data demonstrate that ECD promotes survival upon endoplasmic reticulum stress by increasing GRP78 protein levels to enhance the adaptive folding protein in the endoplasmic reticulum to attenuate PERK signaling.
Results demonstrate that mammalian Ecd plays a role in cell cycle progression via the Rb-E2F pathway.
Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes.
ecdysoneless homolog (Drosophila)
, suppressor of S. cerevisiae gcr2
, protein SGT1
, protein ecdysoneless homolog
, suppressor of GCR2
, protein SGT1 homolog