ECD/SGT1 抗体
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- 抗原 See all ECD/SGT1 (ECD) 抗体
- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ECD/SGT1 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
- 交叉反应 （详细）
- Human. Predicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan and Elephant (based on sequence homology).
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human ECD protein
- 亚型
- IgG2b
- Top Product
- Discover our top product ECD Primary Antibody
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anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibody
ECD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-300) antibodyECD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibodyECD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (C-Term) antibodyECD 适用: 人, 山羊, 马, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 72-121) antibodyECD 适用: 人, 山羊, 马, 兔, Cow, Pig, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or 293T cells. Human testis, spleen or colon.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
- 别名
- ECD (ECD 产品)
- 别名
- GCR2 antibody, HSGT1 antibody, 5730461K03Rik antibody, Hsgt1 antibody, ecdysoneless cell cycle regulator antibody, ecdysoneless homolog (Drosophila) antibody, ECD antibody, Ecd antibody
- 背景
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Ecdysoneless homolog, hSGT1, Human suppressor of GCR two, Protein ecdysoneless homolog, SGT1 protein,ECD / SGT1
Cellular localisation: Nucleus. Cytosol. - 分子量
- 72.76kDa
- 基因ID
- 11319, 631822
- UniProt
- O95905
- 途径
- Regulation of Carbohydrate Metabolic Process
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