Retinoblastoma Binding Protein 8 抗体
(Retinoblastoma Binding Protein 8 (RBBP8))
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Retinoblastoma Binding Protein 8 抗体 (AA 763-792) (FITC) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 763-792) (PE) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 763-792) (APC) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 763-792) (HRP) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 763-792) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 | 人 | 小鼠 Monoclonal |
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| Retinoblastoma Binding Protein 8 抗体 | 人 | 小鼠 Monoclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 126-331) (Biotin) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 126-331) (HRP) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 126-331) (FITC) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 525-575) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (Thr686) | 人, 小鼠 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 763-792) | 人 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 620-897) | 人 | 小鼠 Monoclonal |
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| Retinoblastoma Binding Protein 8 抗体 (pSer327) | 人, 小鼠, 猴 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 293-342) | 人, 小鼠 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (AA 630-679) | 人, 小鼠 | 兔 Polyclonal |
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| Retinoblastoma Binding Protein 8 抗体 (Center) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 763-792
Primary Antibody
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 763-792
Primary Antibody
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 763-792
Primary Antibody
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 763-792
Primary Antibody
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 763-792
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 19E8
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ChIP (Chromatin Immunoprecipitation: 所列应用)
- PLA (Proximity Ligation Assay: 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1-90E-09
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 126-331
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 126-331
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 126-331
Primary Antibody
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 525-575
Primary Antibody
- WB (Western Blotting: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Thr686
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 763-792
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ChIP (Chromatin Immunoprecipitation: 所列应用)
6 references - 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 14-1
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 620-897
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- pSer327
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 293-342
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 630-679
Primary Antibody
- WB (Western Blotting: 有验证图片)
- EIA (Enzyme Immunoassay: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Latest Publications for our Retinoblastoma Binding Protein 8 抗体
: "ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1266-1279, (2018) (PubMed).
: "ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks." in: Molecular cell, Vol. 68, Issue 1, pp. 61-75.e5, (2017) (PubMed).
: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).
: "RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).
: "MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex." in: Nature communications, Vol. 6, pp. 7744, (2015) (PubMed).
: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).
: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).
: "SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage." in: Genes & development, Vol. 26, Issue 11, pp. 1196-208, (2012) (PubMed).
: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." in: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).
: "ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks." in: Molecular cell, Vol. 68, Issue 1, pp. 61-75.e5, (2017) (PubMed).
: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).
: "RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).
: "MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex." in: Nature communications, Vol. 6, pp. 7744, (2015) (PubMed).
: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).
: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).
: "SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage." in: Genes & development, Vol. 26, Issue 11, pp. 1196-208, (2012) (PubMed).
: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." in: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).
Aliases for Retinoblastoma Binding Protein 8 抗体
RB binding protein 8, endonuclease (RBBP8) 抗体retinoblastoma binding protein 8, endonuclease (Rbbp8) 抗体
RB binding protein 8, endonuclease (Rbbp8) 抗体
retinoblastoma binding protein 8 L homeolog (rbbp8.L) 抗体
retinoblastoma binding protein 8 (rbbp8) 抗体
9930104E21Rik 抗体
COM1 抗体
CTIP 抗体
CtIP 抗体
DKFZp469K0714 抗体
JWDS 抗体
RBBP-8 抗体
RBBP8 抗体
RGD1308872 抗体
RIM 抗体
SAE2 抗体
SCKL2 抗体
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