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Retinoblastoma Binding Protein 8 抗体 (C-Term)

The 兔多克隆 anti-Retinoblastoma Binding Protein 8 antibody is suitable to detect Retinoblastoma Binding Protein 8 in samples from 人, Pig, Cow, 犬, 兔, 豚鼠和马. It has been validated for WB.

Host: Rabbit Target Name: RBBP8 Sample Type: Human Fetal Heart Antibody Dilution: 1. (Retinoblastoma Binding Protein 8 抗体 (C-Term))

WB Suggested Anti-RBBP8 Antibody Titration: 0. (Retinoblastoma Binding Protein 8 抗体 (C-Term))

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产品编号 ABIN2784374

发货至: 中国

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Quick Overview for Retinoblastoma Binding Protein 8 抗体 (C-Term) (ABIN2784374)

抗原

See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体

Retinoblastoma Binding Protein 8 (RBBP8)

适用

人, Pig, Cow, 犬, 兔, 豚鼠, 马

宿主

兔

克隆类型

多克隆

标记

This Retinoblastoma Binding Protein 8 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product RBBP8 Primary Antibody

抗原表位
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1
C-Term

原理

RBBP8 Antibody - C-terminal region

序列

ETVDMDCTLV SETVLLKMKK QEQKGEKSSN EERKMNDSLE DMFDRTTHEE

预测反应

Cow: 79%, Dog: 86%, Guinea Pig: 83%, Horse: 79%, Human: 100%, Pig: 100%, Rabbit: 100%

产品特性

This is a rabbit polyclonal antibody against RBBP8. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human RBBP8
anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 452-747) antibody
RBBP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) antibody
RBBP8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 1-300) antibody
RBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 126-331) antibody
RBBP8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (Center) antibody
RBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (pThr847) antibody
RBBP8 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (pThr847) antibody
RBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (pSer327) antibody
RBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (pSer326) antibody
RBBP8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Binding Protein 8 (RBBP8) (AA 763-792), (C-Term) antibody
RBBP8 适用: 人 WB 宿主: 兔 Polyclonal RB34059 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50887-100UG

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

Retinoblastoma Binding Protein 8 (RBBP8)

别名

RBBP8

背景

Background Information: RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Gene Name: Retinoblastoma binding protein 8
Alternative Symbols: RIM, COM1, CTIP, JWDS, SAE2, SCKL2
Protein Name: DNA endonuclease RBBP8 Ensembl ENSP00000382630

分子量

98kDa

基因ID

5932

NCBI登录号

NP_976037

UniProt

A6NKN2

途径

Cell Division Cycle, DNA Damage Repair