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Retinoblastoma Binding Protein 8 抗体 (Center)

RBBP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856639
发货至: 中国
  • 抗原 See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
    Retinoblastoma Binding Protein 8 (RBBP8)
    抗原表位
    • 10
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    Center
    适用
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    宿主
    • 60
    • 3
    克隆类型
    • 60
    • 3
    多克隆
    标记
    • 35
    • 5
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    This Retinoblastoma Binding Protein 8 antibody is un-conjugated
    应用范围
    • 36
    • 25
    • 8
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    Western Blotting (WB)
    产品特性
    Rabbit polyclonal antibody to CtIP (retinoblastoma binding protein 8)
    CtIP antibody [C1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human CtIP. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product RBBP8 Primary Antibody
  • 应用备注
    Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*
    说明

    Positive Control: A431 , H1299 , HeLa , HepG2 , Raji

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Kuo, Li, Stark, Shih, Ann: "RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).

  • 抗原
    Retinoblastoma Binding Protein 8 (RBBP8)
    别名
    CtIP (RBBP8 产品)
    别名
    COM1 antibody, CTIP antibody, JWDS antibody, RIM antibody, SAE2 antibody, SCKL2 antibody, 9930104E21Rik antibody, CtIP antibody, RBBP-8 antibody, RGD1308872 antibody, RBBP8 antibody, DKFZp469K0714 antibody, RB binding protein 8, endonuclease antibody, retinoblastoma binding protein 8, endonuclease antibody, retinoblastoma binding protein 8 L homeolog antibody, retinoblastoma binding protein 8 antibody, RBBP8 antibody, Rbbp8 antibody, rbbp8.L antibody, rbbp8 antibody
    背景
    The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

    Cellular Localization: Nucleus
    分子量
    102 kDa
    基因ID
    5932
    途径
    Cell Division Cycle, DNA Damage Repair
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