RAD51 抗体
(DNA Repair Protein Homolog 1 (RAD51))
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].
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170 results
RAD51
适用: 人, 小鼠
IHC (p), IF (p), IF (cc), ICC, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our RAD51 抗体
: "Genetic determinants of cellular addiction to DNA polymerase theta." in: Nature communications, Vol. 10, Issue 1, pp. 4286, (2020) (PubMed).: "UVB Irradiation Induced Cell Damage and Early Onset of Junbb Expression in Zebrafish." in: Animals : an open access journal from MDPI, Vol. 10, Issue 6, (2020) (PubMed).
: "A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs." in: Cell reports, Vol. 26, Issue 3, pp. 775-787.e5, (2019) (PubMed).
: "Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells." in: eLife, Vol. 8, (2019) (PubMed).
: "Assessing effects of germline exposure to environmental toxicants by high-throughput screening in C. elegans." in: PLoS genetics, Vol. 15, Issue 2, pp. e1007975, (2019) (PubMed).
: "Dibutyl phthalate exposure disrupts the progression of meiotic prophase I by interfering with homologous recombination in fetal mouse oocytes." in: Environmental pollution (Barking, Essex : 1987), Vol. 252, Issue Pt A, pp. 388-398, (2019) (PubMed).
: "BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance." in: Cell reports, Vol. 24, Issue 13, pp. 3513-3527.e7, (2019) (PubMed).
: "Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma." in: Oncotarget, Vol. 9, Issue 4, pp. 4647-4660, (2018) (PubMed).
: "Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling." in: Cell chemical biology, Vol. 25, Issue 6, pp. 677-690.e12, (2018) (PubMed).
: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).
Aliases for RAD51 抗体
RAD51 recombinase (RAD51) 抗体RAD51 recombinase (rad51) 抗体
RAD51 recombinase (Rad51) 抗体
RAS associated with diabetes protein 51 (RAD51) 抗体
RAD51 recombinase L homeolog (rad51.L) 抗体
ATRAD51 抗体
AV304093 抗体
BRCC5 抗体
brcc5 抗体
CRAD51 抗体
F22D1.20 抗体
F22D1_20 抗体
HRAD51 抗体
HsRad51 抗体
HsT16930 抗体
MRMV2 抗体
rad51 抗体
RAD51A 抗体
Rad51a 抗体
rad51a 抗体
RAS associated with diabetes protein 51 抗体
RECA 抗体
Reca 抗体
reca 抗体
RGD1563603 抗体
wu:fb38e12 抗体
xrad51 抗体
zgc:77754 抗体
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