(Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010].
Blanchetot, Tertoolen, Overvoorde, den Hertog: "Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47263-9, (2002) (PubMed).
Aliases for PTPRD 抗体
protein tyrosine phosphatase, receptor type D (PTPRD) 抗体 protein tyrosine phosphatase, receptor type, D (Ptprd) 抗体 receptor-type tyrosine-protein phosphatase delta (LOC100155429) 抗体 protein tyrosine phosphatase, receptor type, D, b (ptprdb) 抗体 protein tyrosine phosphatase, receptor type D S homeolog (ptprd.S) 抗体 1110002J03Rik 抗体 3000002J10Rik 抗体 B230219D21Rik 抗体 HPTP 抗体 HPTPD 抗体 HPTPDELTA 抗体 PTPD 抗体 ptpdelta 抗体 ptprd 抗体 R-PTP-delta 抗体 RPTPDELTA 抗体 rptpdelta 抗体 xptp-d 抗体 zgc:165626 抗体