HPTP antibody, HPTPD antibody, HPTPDELTA antibody, PTPD antibody, RPTPDELTA antibody, 1110002J03Rik antibody, 3000002J10Rik antibody, B230219D21Rik antibody, R-PTP-delta antibody, ptprd antibody, zgc:165626 antibody, ptpdelta antibody, rptpdelta antibody, xptp-d antibody, protein tyrosine phosphatase, receptor type D antibody, protein tyrosine phosphatase, receptor type, D antibody, receptor-type tyrosine-protein phosphatase delta antibody, protein tyrosine phosphatase, receptor type, D, b antibody, protein tyrosine phosphatase, receptor type D S homeolog antibody, PTPRD antibody, Ptprd antibody, LOC100155429 antibody, ptprdb antibody, ptprd.S antibody
背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.,PTPRD,HPTP,HPTPD,HPTPDELTA,PTPD,RPTPDELTA,Signal Transduction,Neuroscience,PTPRD