PTPN21 抗体
(Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008].
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PTPN21
适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our PTPN21 抗体
: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." in: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).: "Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41124-32, (2001) (PubMed).
: "Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis." in: International journal of urology : official journal of the Japanese Urological Association, Vol. 6, Issue 11, pp. 572-7, (2000) (PubMed).
Aliases for PTPN21 抗体
protein tyrosine phosphatase, non-receptor type 21 (PTPN21) 抗体protein tyrosine phosphatase, non-receptor type 21 (Ptpn21) 抗体
Ptp2E 抗体
PTPD1 抗体
PTPRL10 抗体
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