PTPN21 抗体 (C-Term)
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- 抗原 See all PTPN21 抗体
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 斑马鱼, 豚鼠, 马, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN21 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FWQMVWEQGI AIIAMVTAEE EGGREKSFRY WPRLGSRHNT VTYGRFKITT
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PTPN21. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PTPN21
- Top Product
- Discover our top product PTPN21 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1174 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
- 别名
- PTPN21 (PTPN21 产品)
- 别名
- PTPD1 antibody, PTPRL10 antibody, Ptp2E antibody, protein tyrosine phosphatase, non-receptor type 21 antibody, PTPN21 antibody, Ptpn21 antibody
- 背景
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
Alias Symbols: PTPD1, PTPRL10
Protein Interaction Partner: KIF1C, AKAP1, TEC, BMX, SRC,
Protein Size: 1174 - 分子量
- 133 kDa
- 基因ID
- 11099
- NCBI登录号
- NM_007039, NP_008970
- UniProt
- Q16825
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