PTPN21 抗体 (AA 751-780)
PTPN21
适用: 人
WB, IHC (p)
宿主: 兔
Polyclonal
RB0623-0624
unconjugated
(1 reference)-
- 抗原 See all PTPN21 抗体
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
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抗原表位
- AA 751-780
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN21 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PTPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human PTPD1.
- 克隆位点
- RB0623-0624
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PTPN21 Primary Antibody
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21) (AA 983-1176) antibody
PTPN21 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21) (AA 981-1174) antibodyPTPN21 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." in: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).
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: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." in: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).
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- 抗原
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
- 别名
- PTPD1 (PTPN21 产品)
- 别名
- PTPD1 antibody, PTPRL10 antibody, Ptp2E antibody, protein tyrosine phosphatase, non-receptor type 21 antibody, PTPN21 antibody, Ptpn21 antibody
- 背景
- PTPD1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
- 分子量
- 133281
- 基因ID
- 11099
- NCBI登录号
- NP_008970
- UniProt
- Q16825
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