PTPN12 抗体
(Protein Tyrosine Phosphatase G1 (PTPN12))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
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60 results
PTPN12
适用: 人, 小鼠, 大鼠
WB
宿主: 兔
Monoclonal
A502
unconjugated
Recombinant Antibody
PTPN12
适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠
WB, IHC, IP, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our PTPN12 抗体
: "Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer." in: Oncotarget, Vol. 6, Issue 13, pp. 11704-13, (2015) (PubMed).
: "PTPN12 promotes resistance to oxidative stress and supports tumorigenesis by regulating FOXO signaling." in: Oncogene, Vol. 33, Issue 8, pp. 1047-54, (2014) (PubMed).
: "PTPN12 promotes resistance to oxidative stress and supports tumorigenesis by regulating FOXO signaling." in: Oncogene, Vol. 33, Issue 8, pp. 1047-54, (2014) (PubMed).
Aliases for PTPN12 抗体
protein tyrosine phosphatase, non-receptor type 12 (PTPN12) 抗体protein tyrosine phosphatase, non-receptor type 12 (Ptpn12) 抗体
P19-PTP 抗体
PTP-P19 抗体
PTP-PEST 抗体
PTPG1 抗体
Ptpg1 抗体
RKPTP 抗体
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