TNF alpha 蛋白
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北京 101111
Quick Overview for TNF alpha 蛋白 (ABIN988275)
抗原
See all TNF alpha 蛋白生物活性
宿主
资源
纯度
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序列
- VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVV PSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAEINRPD YLDFAESGQV YFGIIA
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产品特性
- Plate 3*104 cell per well in 96-well plates in RPMI 1640 medium with 10%FBS for 24 h. Sub confluent cells were starved 4 h in RPMI 1640 medium with 2%FBS. Standard and Sample 2-human TNF- alpha were added and cell viability measured 24 h later by addition of CellTiter 96® AQueous Non-Radioactive Cell Proliferation Assay reagent (MTS). The ED50 for this effect is typically 0.02-0.08ng/ml.
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内毒素水平
- level is less than 0.1 ng per myg (1EU/myg) of TNF-alpha
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 150,642.20 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) protein (His-Avi Tag,Biotin)
TNF alpha 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) protein (His-Avi Tag)TNF alpha 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) protein (His tag)TNF alpha 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Tumor Necrosis Factor alpha (TNF alpha) (AA 1-233) protein (His tag)custom-made TNF alpha 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor alpha (TNF alpha) (AA 1-235) protein (His tag)custom-made TNF alpha 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) (Active) proteinHPLC verified TNF alpha 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) (Active) protein (Biotin)TNF alpha 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) (Active) protein (His tag,AVI tag,Biotin)TNF alpha 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (Active) proteinTNF alpha 宿主: 兔 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (Active) proteinTNF alpha 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE Active
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- -20 °C
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: "Glycosylation profiling of therapeutic antibodies in serum samples using a microfluidic CD platform and MALDI-MS." in: Journal of the American Society for Mass Spectrometry, Vol. 24, Issue 7, pp. 1053-63, (2013) (PubMed).
: "CNK1 promotes invasion of cancer cells through NF-kappaB-dependent signaling." in: Molecular cancer research : MCR, Vol. 8, Issue 3, pp. 395-406, (2010) (PubMed).
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: "Glycosylation profiling of therapeutic antibodies in serum samples using a microfluidic CD platform and MALDI-MS." in: Journal of the American Society for Mass Spectrometry, Vol. 24, Issue 7, pp. 1053-63, (2013) (PubMed).
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- Tumor Necrosis Factor-alpha (TNF-alpha)
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背景
- TNF-alpha plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease. TNF alpha-1a is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Synonym: TNF-alpha. Formulation: Lyophilized from a 0.2 mym filtered solution in PBS.
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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