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IL-6 蛋白

IL6 宿主: 猕猴 宿主: 大肠杆菌(E. Coli) > 97 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN988090
发货至: 中国
  • 抗原 See all IL-6 (IL6) 蛋白
    IL-6 (IL6) (Interleukin 6 (IL6))
    生物活性
    Active
    宿主
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    猕猴
    资源
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    大肠杆菌(E. Coli)
    序列
    MAPVLPGEDS KNVAAPHSQP LTSSERIDKH IRYILDGISA LRKETCNRSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEDTCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PEPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSNL RALRQ
    产品特性
    The ED50 was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1.0× 107 units/mg.
    纯度
    > 97 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rRhIL-6 as determined by LAL method
    Top Product
    Discover our top product IL6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
    储存条件
    4 °C
  • 抗原
    IL-6 (IL6) (Interleukin 6 (IL6))
    别名
    Interleukin-6 (IL-6) (IL6 产品)
    背景
    IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rª and gp130. Synonym: Interleukin-6 (IL-6), Rhesus Macaque. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
    分子量
    Approximately 21.1 kDa, a single non-glycosylated polypeptide chain containing 186 amino acids.
    途径
    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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