Sonic Hedgehog Protein (SHH)
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北京 101111
Quick Overview for Sonic Hedgehog Protein (SHH) (ABIN935799)
抗原
See all Sonic Hedgehog (SHH) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- IVIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKISRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRALDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG
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产品特性
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Purified recombinant Human Sonic Hedgehog protein
Expression System: E.coli
Bioactivity: Determined by its ability to induce alkaline phosphatase production by C3H/10T1/2 (CCL-226) cells. The expected ED50 for this effect is 0.8-1.0 ?g/mL. -
过滤
- 0.2 μm filtered
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内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- Supplied as a lyophilized powder. Sterile filtered through a 0.2 micron filter. Lyophilized from 1x PBS.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C to -80 °C for long term storage.
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- Sonic Hedgehog (SHH)
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别名
- Sonic Hedgehog
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背景
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Sonic the hedgehog homolog is one of three proteins in the mammalian signaling pathway family called hedgehog, the others being desert hedgehog and Indian hedgehog. SHH is the best studied ligand of the hedgehog signaling pathway. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain.
Alternative Names: SHH protein -
途径
- Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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