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Sonic Hedgehog Protein (SHH) (AA 25-198, Cys25IleIle-Mutant)

SHH 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN2018373
发货至: 中国
  • 抗原 See all Sonic Hedgehog (SHH) 蛋白
    Sonic Hedgehog (SHH)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 25-198, Cys25IleIle-Mutant
    宿主
    • 15
    • 12
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    • 2
    • 2
    • 2
    • 1
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    • 1
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    小鼠
    资源
    • 18
    • 18
    • 6
    • 2
    • 1
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    大肠杆菌(E. Coli)
    产品特性
    ED50<1.0 μg/mL, measured by its ability to induce alkaline phosphatase production by C3H/10T1/2 (CCL-226) Cells, corresponding to a specific activity of>1.0× 10^3 units/mg.
    纯度
    > 95 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product SHH 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant mouseSonic Hedgehog(rmShh)remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmShhshould be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
    有效期
    6 months
  • 抗原
    Sonic Hedgehog (SHH)
    Abstract
    SHH 产品
    别名
    HHG1 Protein, HLP3 Protein, HPE3 Protein, MCOPCB5 Protein, SMMCI Protein, TPT Protein, TPTPS Protein, 9530036O11Rik Protein, Dsh Protein, Hhg1 Protein, Hx Protein, Hxl3 Protein, M100081 Protein, fc83d08 Protein, shh Protein, syu Protein, vhh-1 Protein, vhh1 Protein, wu:fc83d08 Protein, Xhh Protein, hedgehog Protein, xshh Protein, SHH Protein, twh Protein, twhh Protein, sonic hedgehog Protein, sonic hedgehog a Protein, sonic hedgehog L homeolog Protein, sonic hedgehog protein A Protein, sonic hedgehog b Protein, SHH Protein, Shh Protein, shha Protein, shh.L Protein, shh Protein, shhb Protein
    背景
    Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are threerelatedHh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93 % identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body. Recombinant mouseSonic Hedgehog(rmShh) produced in E.coli is a single non-glycosylated polypeptide chain containing 176 amino acids. A fully biologically active molecule, rmShh,is obtained by proprietary chromatographic techniques with a molecular mass of 19.8 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Hhg1
    分子量
    19.8kDa, observed by reducing SDS-PAGE.
    UniProt
    Q62226
    途径
    Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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