NGFB 蛋白
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北京 101111
Quick Overview for NGFB 蛋白 (ABIN935676)
抗原
See all NGFB 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR
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产品特性
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Purified recombinant Human beta NGF protein
Expression System: E.coli
Bioactivity: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED50 is 1 x 10^6 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- Supplied lyophilized with no additives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- NGFB (Nerve Growth Factor beta (NGFB))
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别名
- beta NGF
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背景
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Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival.
Alternative Names: beta-NGF protein, Nerve Growth factor protein, NGF-beta protein -
分子量
- 13.5 kDa
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途径
- NF-kappaB Signaling, RTK signaling, Regulation of Cell Size
抗原
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