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IL12 蛋白

IL12 宿主: 人 宿主: CHO Cells Recombinant > 98 % pure Active
产品编号 ABIN935473
发货至: 中国
  • 抗原 See all IL12 蛋白
    IL12 (Interleukin 12 (IL12))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 18
    • 9
    • 5
    • 1
    资源
    • 14
    • 5
    • 4
    • 4
    • 2
    • 1
    CHO Cells
    序列
    RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS
    产品特性
    Purified recombinant Human IL12 protein
    Expression System: CHO cells
    Bioactivity: The ED50 was determined by the induction of IFN-gamma from NK cells co-stimulated with IL-18 is ? 1.0 ng/mL, corresponding to a specific activity of ? 1 x 10^6 units/mg.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL12 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 1 xPBS to a concentration of 0.2 mg/mL.
    缓冲液
    Lyophilized from 0.5 x PBS, pH 7.2.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    RT/-20 °C
  • 抗原
    IL12 (Interleukin 12 (IL12))
    别名
    IL12 (IL12 产品)
    别名
    CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, LOC100217488 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p40 Protein, IL12B Protein, IL-12 p35 Protein, interleukin 12B Protein, interleukin 12A Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12B Protein, IL12A Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein
    背景
    IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells.
    Alternative Names: NKSF protein, IL-12, Cytotoxic lymphocyte maturation factor protein, IL-12 protein, TSF protein, IL 12, CLMF protein, Interleukin 12 protein, IL 12 protein, CTL maturation factor protein, TCMF protein, IL-12 protein, IL12
    分子量
    75 kDa
    途径
    JAK/STAT Signaling, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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