IL-1 beta 蛋白
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北京 101111
Quick Overview for IL-1 beta 蛋白 (ABIN935468)
抗原
See all IL-1 beta (IL1B) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
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产品特性
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Purified recombinant Human IL1 beta protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by Mouse D10S cells is ? 1.0 pg/mL, corresponding to a specific activity of ? 1 x 10^9 units/mg. -
过滤
- 0.2 μm filtered
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内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 1, beta (IL1B) (AA 117-269) protein (His-Avi Tag)
IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein (Biotin,His-Avi Tag)IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 1, beta (IL1B) (AA 1-269) protein (GST tag)IL1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1, beta (IL1B) (AA 117-269) protein (Fc Tag)IL1B 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 1, beta (IL1B) (AA 170-269) protein (GST tag)IL1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein (His tag)IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Interleukin 1, beta (IL1B) (AA 118-269) (Active) protein (His tag)IL1B 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Interleukin 1, beta (IL1B) (Active) proteinIL1B 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 1, beta (IL1B) (Active) proteinIL1B 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 98 % as determined by SDS-PAGE Active
Interleukin 1, beta (IL1B) (AA 106-267) protein (His tag)IL1B 宿主: 小鸡 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. When dissolved, dilute further into aqueous buffered solutions.
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缓冲液
- Sterile filtered through a 0.2 µm filter. Lyophilized from 10 mM Tris, pH 8.2.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
- IL1 beta
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背景
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IL1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.
Alternative Names: IL1, Leukocyte Endogenous Mediator protein, Lymphocyte-activating factor protein, LAF protein, Mononuclear Cell Factor protein, MCF protein, Catabolin protein, IL 1, IL-1 protein, Interleukin 1 beta protein, IL 1 protein, Endogenous Pyrogen protein, EP protein, LEM protein, IL-1 beta protein, IL-1 -
分子量
- 17.3 kDa
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途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
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