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IL-4 蛋白

IL4 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 96 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN871822
发货至: 中国
  • 抗原 See all IL-4 (IL4) 蛋白
    IL-4 (IL4) (Interleukin 4 (IL4))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
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    小鼠
    资源
    • 38
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    大肠杆菌(E. Coli)
    序列
    MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDYS
    纯度
    > 96 % by SDS-PAGE and HPLC analyses.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 1EU/µg of rmIL-4 as determined by LAL method.
    Top Product
    Discover our top product IL4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C/-20 °C
  • 抗原
    IL-4 (IL4) (Interleukin 4 (IL4))
    别名
    IL-4 (IL4 产品)
    别名
    IL4 Protein, IL-4 Protein, BCGF-1 Protein, BCGF1 Protein, BSF-1 Protein, BSF1 Protein, Il-4 Protein, Il4e12 Protein, IL2 Protein, interleukin 4 Protein, IL4 Protein, Il4 Protein
    背景
    Interleukin-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy.
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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