HRAS Protein (AA 1-186)
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Quick Overview for HRAS Protein (AA 1-186) (ABIN7939166)
抗原
See all HRAS 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 1-186
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原理
- Recombinant HRAS (1-186) protein
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant HRAS (1-186) protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- HRAS (HRas proto-oncogene, GTPase (HRAS))
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别名
- HRAS
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背景
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Protein Background: HRAS (GTPase HRas) protein encoded by HRAS is a GTPase. HRas is a small G protein that belongs to the small GTPase superfamily. When HRas is combined with guanosine triphosphate, it will bind to Raf kinases such as c-Raf and further activate MAPK/ERK path. Mutations in this gene have been associated with a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma.
Short Description: Recombinant HRAS (1-186) protein that includes amino acids 1-186 of human HRAS protein (accession number NP_005334.1) was expressed in E. coli cells with an C-terminal 6xHis tag. The molecular weight of the protein is 22.06 kDa.
Aliases: GTPase HRas, HRAS1, HRas proto-oncogene, GTPase, H-Ras
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling
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