IL-1 beta 蛋白
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北京 101111
Quick Overview for IL-1 beta 蛋白 (ABIN7937156)
抗原
See all IL-1 beta (IL1B) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Rat Interleukin-1 beta
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序列
- MVPIRQLHCR LRDEQQKCLV LSDPCELKAL HLNGQNISQQ VVFSMSFVQG ETSNDKIPVA LGLKGLNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKTK VEFESAQFPN WYISTSQAEH RPVFLGNSNG RDIVDFTMEP VSS
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 1 EU/ug of rRtIL-1β as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 x107 IU/mg.
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说明
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Approximately 17.3 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4, with 5 % trehalose, 0.02 % Tween-20.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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有效期
- 12 months
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
- Interleukin-1 beta
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分子量
- 17.3 kDa
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UniProt
- Q63264
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途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
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