IL-1 beta 蛋白
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北京 101111
Quick Overview for IL-1 beta 蛋白 (ABIN7849736)
抗原
See all IL-1 beta (IL1B) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human Interleukin-1beta, IL1B Protein
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内毒素水平
- < 0.1 ng/μg (1 EU/μg) by LAL test
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Interleukin 1, beta (IL1B) (AA 117-269) protein (His-Avi Tag)
IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein (Biotin,His-Avi Tag)IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 1, beta (IL1B) (AA 1-269) protein (GST tag)IL1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1, beta (IL1B) (AA 117-269) protein (Fc Tag)IL1B 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 1, beta (IL1B) (AA 170-269) protein (GST tag)IL1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein (His tag)IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Interleukin 1, beta (IL1B) (AA 118-269) (Active) protein (His tag)IL1B 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Interleukin 1, beta (IL1B) (Active) proteinIL1B 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % as determined by SDS-PAGE Active
Interleukin 1, beta (IL1B) (Active) proteinIL1B 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 98 % as determined by SDS-PAGE Active
Interleukin 1, beta (IL1B) (AA 106-267) protein (His tag)IL1B 宿主: 小鸡 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized,Each vial contains 10 mM Phosphate bufferand 200 mM NaCl( pH 7.0) without preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Ship at 4°C. Upon receipt,store at -20°C for long term. Avoid repeated freeze and thaw cycles.
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
- IL1B
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背景
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Synonyms: Interleukin-1 beta, IL1B, IL-1 beta, Catabolin, IL1F2, IL-1B, IL-1, IL1-BETA, IL1F2, interleukin 1 beta.
Description: Recombinant human IL-1 beta protein.
Background: Interleukin-1β (IL-1β) is a potent stimulator of bone resorption whose gene is mapped to 2q14, and has been implicated in the pathogenesis of high bone turnover and osteoporosis. It can reset glucose homeostasis at central levels. It cause oligodendrocyte death in coculture with astrocytes and microglia, and also can cause nuclear export of a specific NCOR corepressor complex, resulting in derepression of a specific subset of nuclear factor-kappa-B (NFKB)-regulated genes. Pathak et al. (2011) proposed that IL1B blockade may be a viable therapy for patients with autoimmune inner ear disease or sensorineural hearing loss that fail to respond to corticosteroids.
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途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
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