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Osteoprotegerin Protein (Fc Tag,His tag)

TNFRSF11B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 87 % by SDS-PAGE. Active
产品编号 ABIN7534823
发货至: 中国
  • 抗原 See all Osteoprotegerin (TNFRSF11B) 蛋白
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    小鼠
    资源
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This Osteoprotegerin protein is labelled with Fc Tag,His tag.
    原理
    Active Recombinant Mouse TNFRSF11B/Osteoprotegerin Protein
    序列
    MNKWLCCALL VLLDIIEWTT QETLPPKYLH YDPETGHQLL CDKCAPGTYL KQHCTVRRKT LCVPCPDHSY TDSWHTSDEC VYCSPVCKEL QSVKQECNRT HNRVCECEEG RYLEIEFCLK HRSCPPGSGV VQAGTPERNT VCKKCPDGFF SGETSSKAPC IKHTNCSTFG LLLIQKGNAT HDNVCSGNRE ATQKCGIDVT LCEEAFFRFA VPTKIIPNWL SVLVDSLPGT KVNAESVERI KRRHSSQEQT FQLLKLWKHQ NRDQEMVKKI IQDIDLCESS VQRHLGHSNL TTEQLLALME SLPGKKISPE EIERTRKTCK SSEQLLKLLS LWRIKNGDQD TLKGLMYALK HLKTSHFPKT VTHSLRKTMR FLHSFTMYRL YQKLFLEMIG NQVQSVKISC L
    特异性
    Met1-Leu401
    纯度
    > 87 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    1.Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human TNFSF11 at 2 μg/mL (100 μL/well) can bind Recombinant Mouse TNFRSF11B with a linear range of 3-10 ng/mL.|2.Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is 0.13-0.54 ng/mL in the presence of 20 ng/mL Recombinant Human TRAIL/TNFSF10.
    Top Product
    Discover our top product TNFRSF11B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    别名
    TNFRSF11B/Osteoprotegerin (TNFRSF11B 产品)
    别名
    CD254 Protein, ODF Protein, OPGL Protein, OPTB2 Protein, RANKL Protein, TRANCE Protein, hRANKL2 Protein, sOdf Protein, OCIF Protein, OPG Protein, TR1 Protein, Opg Protein, ocif Protein, opg Protein, tr1 Protein, TNF superfamily member 11 Protein, TNF receptor superfamily member 11b Protein, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Protein, TNF receptor superfamily member 11B Protein, tumor necrosis factor receptor superfamily member 11b S homeolog Protein, tumor necrosis factor receptor superfamily, member 11b Protein, TNFSF11 Protein, TNFRSF11B Protein, Tnfrsf11b Protein, tnfrsf11b.S Protein
    物质类
    Chemical
    背景
    TNFRSF11B,OCIF,OPG,Osteoprotegerin,TR1,TNFRSF11B
    基因ID
    18383
    UniProt
    O08712
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