TFF1 Protein (pSer2) (His tag)
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- 抗原 See all TFF1 蛋白
- TFF1 (Trefoil Factor 1 (TFF1))
- 蛋白类型
- Recombinant
- 产品特性
- pSer2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TFF1 protein is labelled with His tag.
- 原理
- Recombinant Human BCEI/PS2/TFF1 Protein
- 序列
- EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF
- 特异性
- Glu25-Phe84
- 纯度
- > 97 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 0.001 EU/μg
- Top Product
- Discover our top product TFF1 蛋白
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Trefoil Factor 1 (TFF1) (Active) protein
TFF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Trefoil Factor 1 (TFF1) (AA 22-87) protein (Fc Tag)TFF1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Trefoil Factor 1 (TFF1) (AA 25-84) protein (Fc Tag)TFF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Trefoil Factor 1 (TFF1) (AA 1-84) protein (GST tag)TFF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Trefoil Factor 1 (TFF1) (AA 25-84) protein (His tag)TFF1 宿主: 人 宿主: 酵母菌 Recombinant > 90 % ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 浓度
- 1.1 mg/mL
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- TFF1 (Trefoil Factor 1 (TFF1))
- 别名
- BCEI//TFF1 (TFF1 产品)
- 别名
- BCEI Protein, D21S21 Protein, HP1.A Protein, HPS2 Protein, pNR-2 Protein, pS2 Protein, Bcei Protein, PS2 Protein, bcei Protein, d21s21 Protein, hp1.a Protein, hps2 Protein, p1 Protein, p1-a Protein, pnr-2 Protein, ps2 Protein, tff1 Protein, xP1 Protein, xp1-L Protein, xp1 Protein, TFF1 Protein, Ps2 Protein, trefoil factor 1 Protein, trefoil factor 1 S homeolog Protein, trefoil factor 1, gene 2 S homeolog Protein, TFF1 Protein, Tff1 Protein, tff1.S Protein, tff1.2.S Protein, LOC100358238 Protein
- 背景
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Description: Trefoil Factor 1 (TFF1), also known as pS2, is one of three structurally related secreted proteins that contain trefoil domains. These domains adopt a three-leaved conformation held together by conserved intrachain disulfide bonds. TFF1 is an approximately 7 kDa peptide that plays an important role in epithelial regeneration and wound healing (1). Mature human TFF1 shares 67 % amino acid sequence identity with mouse and rat TFF1. It is expressed by goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells (2-5). TFF1 is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and form non-covalent complexes with the mucin MUC5AC (4, 6-8). Copper enhances TFF1 homodimerization as well as its ability to promote epithelial cell motility, wound healing, and the colonization of H. pylori in stomach and colon epithelia (9, 10). TFF1 is down-regulated during the progression from gastritis to gastric dysplasia to gastric cancer, although it is up-regulated in breast and prostate cancers (11-13). TFF1 inhibits the formation of calcium oxalate crystals, and its excretion in the urine is reduced in patients with kidney stones (14).
Name: pS2, BCEI, HPS2, HP1.A, pNR-2, D21S21,TFF1
- 基因ID
- 7031
- UniProt
- P04155
- 途径
- EGFR Signaling Pathway
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