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TFF1 Protein (His tag)

TFF1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319431
发货至: 中国
  • 抗原 See all TFF1 蛋白
    TFF1 (Trefoil Factor 1 (TFF1))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 5
    • 2
    • 1
    • 1
    资源
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    人细胞
    标记
    This TFF1 protein is labelled with His tag.
    原理
    Recombinant Human Trefoil Factor 1/TFF1 Protein (His Tag)
    序列
    Glu25-Phe84
    产品特性
    Recombinant Human TFF1 is produced by our Mammalian expression system and the target gene encoding Glu25-Phe84 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TFF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TFF1 (Trefoil Factor 1 (TFF1))
    别名
    Trefoil Factor 1/TFF1 (TFF1 产品)
    别名
    BCEI Protein, D21S21 Protein, HP1.A Protein, HPS2 Protein, pNR-2 Protein, pS2 Protein, Bcei Protein, PS2 Protein, bcei Protein, d21s21 Protein, hp1.a Protein, hps2 Protein, p1 Protein, p1-a Protein, pnr-2 Protein, ps2 Protein, tff1 Protein, xP1 Protein, xp1-L Protein, xp1 Protein, TFF1 Protein, Ps2 Protein, trefoil factor 1 Protein, trefoil factor 1 S homeolog Protein, trefoil factor 1, gene 2 S homeolog Protein, TFF1 Protein, Tff1 Protein, tff1.S Protein, tff1.2.S Protein, LOC100358238 Protein
    背景

    Background: Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains. TFF1 is an approximately 7 kDa peptide that plays an important role in epithelial regeneration and wound healing. It is highly expressed in goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells. By conserving intrachain disulfide bonds, human TFF1 formed a three-leaved conformation held together.It is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and form non-covalent complexes with the mucin MUC5AC. TFF1 is down-regulated during the progression from gastritis to gastric dysplasia to gastric cancer, although it is up-regulated in breast and prostate cancers.

    Synonym: Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, hP1.A, Protein Ps2, TFF1, BCEI, PS2

    分子量
    7.5 kDa
    UniProt
    P04155
    途径
    EGFR Signaling Pathway
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