MOG Protein (His tag)
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- 抗原 See all MOG 蛋白
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MOG protein is labelled with His tag.
- 原理
- Active Recombinant Human Myelin-oligodendrocyte glycoprotein/MOG Protein
- 序列
- GQFRVIGPRH PIRALVGDEV ELPCRISPGK NATGMEVGWY RPPFSRVVHL YRNGKDQDGD QAPEYRGRTE LLKDAIGEGK VTLRIRNVRF SDEGGFTCFF RDHSYQEEAA MELKVEDPFY WVSPG
- 特异性
- Gly30-Gly154
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <0.1EU/μg
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human MOG at 1 μg/mL (100 μL/well) can bind Myelin oligodendrocyte glycoprotein Rabbit mAb with a linear range of 0.98-2.5 ng/mL
- Top Product
- Discover our top product MOG 蛋白
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Myelin Oligodendrocyte Glycoprotein (MOG) (AA 1-295) protein (GST tag)
MOG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- 别名
- Myelin-oligodendrocyte glycoprotein/MOG (MOG 产品)
- 别名
- MOGIG2 Protein, NRCLP7 Protein, B230317G11Rik Protein, MOG Protein, myelin oligodendrocyte glycoprotein Protein, MOG Protein, Mog Protein
- 背景
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Description: Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1 % total proteins) in the oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce demyelinating multiple sclerosis-like diseases in experimental animals.
Name: BTN6, BTNL11, MOGIG2, NRCLP7,MOG,BTNL11,MOGIG2,NRCLP7
- 基因ID
- 4340
- UniProt
- Q16653
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