MOG Protein (AA 30-149) (His tag)
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- 抗原 See all MOG 蛋白
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- 蛋白类型
- Recombinant
- 产品特性
- AA 30-149
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This MOG protein is labelled with His tag.
- 原理
- Recombinant Human MOG Protein (aa 30-149, His Tag)
- 序列
- Gly 30-Tyr 149
- 产品特性
- A DNA sequence encoding the extracellular domain of human MOG (NP_996532.2) (Gly 30-Tyr 149) was expressed, fused with a polyhistidine tag at the C-terminus and an additional Met at the N-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MOG 蛋白
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Myelin Oligodendrocyte Glycoprotein (MOG) (AA 1-295) protein (GST tag)
MOG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- 别名
- MOG (MOG 产品)
- 别名
- MOGIG2 Protein, NRCLP7 Protein, B230317G11Rik Protein, MOG Protein, myelin oligodendrocyte glycoprotein Protein, MOG Protein, Mog Protein
- 背景
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Background: Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1 % total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.
Synonym: Myelin-Oligodendrocyte Glycoprotein, MOG,BTN6,BTNL11,MOGIG2,NRCLP7
- 分子量
- 15 kDa
- NCBI登录号
- NP_996532
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