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MANF Protein (His tag)

MANF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 92 % by SDS-PAGE.
产品编号 ABIN7533798
发货至: 中国
  • 抗原 See all MANF 蛋白
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    蛋白类型
    Recombinant
    宿主
    • 12
    • 2
    • 1
    • 1
    资源
    • 4
    • 3
    • 2
    • 2
    • 2
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    • 1
    大肠杆菌(E. Coli)
    标记
    This MANF protein is labelled with His tag.
    原理
    Recombinant Human MANF Protein
    序列
    LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL
    特异性
    Leu25-Leu182
    纯度
    > 92 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 1.0 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product MANF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 20 mM PIPES, 500 mM NaCl, pH 6.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    别名
    MANF (MANF 产品)
    别名
    ARMET Protein, ARP Protein, 3230402M22Rik Protein, AA407711 Protein, AA408789 Protein, AA673178 Protein, Armet Protein, D17914 Protein, D18Mgi17 Protein, MANF Protein, RBM15B Protein, ARP-like Protein, CG7013 Protein, DmMANF Protein, Dmel\\CG7013 Protein, anon-EST:ParkEST188 Protein, arp Protein, armet Protein, im:6909481 Protein, zgc:153327 Protein, manf Protein, mesencephalic astrocyte derived neurotrophic factor Protein, mesencephalic astrocyte-derived neurotrophic factor Protein, RNA binding motif protein 15B Protein, Mesencephalic astrocyte-derived neurotrophic factor Protein, mesencephalic astrocyte-derived neurotrophic factor S homeolog Protein, MANF Protein, Manf Protein, RBM15B Protein, manf Protein, manf.S Protein
    背景

    Description: The protein is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing this protein increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.

    Name: MANF,ARMET,ARP

    基因ID
    7873
    UniProt
    P55145
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