Macrophage Scavenger Receptor 1 Protein (MSR1) (His tag)
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- 抗原 See all Macrophage Scavenger Receptor 1 (MSR1) 蛋白
- Macrophage Scavenger Receptor 1 (MSR1)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Macrophage Scavenger Receptor 1 protein is labelled with His tag.
- 原理
- Active Recombinant Human MSR1/CD204 Protein
- 序列
- KWETKNCSVS STNANDITQS LTGKGNDSEE EMRFQEVFME HMSNMEKRIQ HILDMEANLM DTEHFQNFSM TTDQRFNDIL LQLSTLFSSV QGHGNAIDEI SKSLISLNTT LLDLQLNIEN LNGKIQENTF KQQEEISKLE ERVYNVSAEI MAMKEEQVHL EQEIKGEVKV LNNITNDLRL KDWEHSQTLR NITLIQGPPG PPGEKGDRGP TGESGPRGFP GPIGPPGLKG DRGAIGFPGS RGLPGYAGRP GNSGPKGQKG EKGSGNTLTP FTKVRLVGGS GPHEGRVEIL HSGQWGTICD DRWEVRVGQV VCRSLGYPGV QAVHKAAHFG QGTGPIWLNE VFCFGRESSI EECKIRQWGT RACSHSEDAG VTCTL
- 特异性
- Lys77-Leu451
- 纯度
- > 90 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- 1.Measured by its binding ability in a functional ELISA.Immobilized Human MSR1 Protein at 1μg/mL (100 μL/well) can bind MSR1 Rabbit pAb with a linear range of 0.76-2.88 ng/mL.|2.Measured by its binding ability in a functional ELISA. Immobilized Human A-I/APOA1 at 5μg/mL (100 μL/well) can bind Human MSR1/CD204 with a linear range of 1-49.4ng/mL.
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- Discover our top product MSR1 蛋白
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Macrophage Scavenger Receptor 1 (MSR1) (AA 77-451) protein (His tag)
MSR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Scavenger Receptor 1 (MSR1) (AA 121-220) protein (GST tag)MSR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Macrophage Scavenger Receptor 1 (MSR1) protein (His tag)MSR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Macrophage Scavenger Receptor 1 (MSR1) protein (Fc Tag)MSR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Macrophage Scavenger Receptor 1 (MSR1) (AA 1-451) protein (Strep Tag)Crystallography grade MSR1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Macrophage Scavenger Receptor 1 (MSR1) (AA 1-458) protein (Strep Tag)Crystallography grade MSR1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Macrophage Scavenger Receptor 1 (MSR1) (AA 77-451) protein (His tag)Crystallography grade MSR1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Scavenger Receptor 1 (MSR1) (AA 79-458) protein (His tag)Crystallography grade MSR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Scavenger Receptor 1 (MSR1) protein (Myc-DYKDDDDK Tag)MSR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- 抗原
- Macrophage Scavenger Receptor 1 (MSR1)
- 别名
- MSR1/CD204 (MSR1 产品)
- 别名
- CD204 Protein, SCARA1 Protein, SR-A Protein, SRA Protein, phSR1 Protein, phSR2 Protein, MRS-A Protein, MSR Protein, MSR-A Protein, SR-AI Protein, SR-AII Protein, Scara1 Protein, Scvr Protein, MSR1 Protein, RGD1564316 Protein, macrophage scavenger receptor 1 Protein, scavenger receptor class A member 5 Protein, MSR1 Protein, Msr1 Protein, SCARA5 Protein
- 背景
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Description: This protein is the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
Name: CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII, SRA, phSR1, phSR2,MSR1,SCARA1,SR-A,SR-AI,SR-AII,SR-AIII,SRA,phSR1,phSR2
- 基因ID
- 4481
- UniProt
- P21757
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